McCullough R W, Gandsman E J, Litchman H E, Schatz S L
Department of Bio Med, Radiation Biology, Chemistry, Brown University, Providence, RI 02194.
Int Orthop. 1988;12(4):317-22. doi: 10.1007/BF00317831.
We report a retrospective study of eighteen patients with pain in the knee or ankle, eleven of whom had osteochondritis dissecans. In these patients the bone-flow time-activity curves were observed after an intravenous injection of a bolus of 99mTc MDP. The curves varied according to the severity of the clinical signs and symptoms. The diagnosis rate was 29% with static scintigraphy and this improved to 57% when dynamic flow studies were used. A positive pattern in the dynamic study together with radiographs and static scintigraphs raised the diagnosis rate to 100%; the sensitivity was 90%. These preliminary results show that dynamic bone scintigraphy holds promise as a technique for identification and management of this condition.
我们报告了一项针对18例膝关节或踝关节疼痛患者的回顾性研究,其中11例患有剥脱性骨软骨炎。对这些患者静脉注射大剂量99mTc MDP后观察骨血流时间-活性曲线。曲线根据临床体征和症状的严重程度而有所不同。静态骨闪烁显像的诊断率为29%,而使用动态血流研究时这一诊断率提高到了57%。动态研究中的阳性表现结合X线片和静态骨闪烁显像,诊断率提高到了100%;敏感性为90%。这些初步结果表明,动态骨闪烁显像有望成为识别和处理这种疾病的一项技术。