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静脉内平滑肌瘤病所致非血栓性肺栓塞:一例报告

Nonthrombotic pulmonary embolism caused by intravenous leiomyomatosis: A case report.

作者信息

Wu Yi-Hsiao, Lee Yung-Tsai, Lee Chuin-I, Tzeng Yun-Hsuan, Wei Jeng

机构信息

Department of Cardiovascular Surgery, Zuoying Branch of Kaohsiung Armed Forces General Hospital, Kaohsiung City.

Heart Center, Cheng-Hsin General Hospital, Taipei.

出版信息

Medicine (Baltimore). 2019 Jan;98(3):e14118. doi: 10.1097/MD.0000000000014118.

Abstract

RATIONALE

Pulmonary embolism is a potentially devastating medical condition. Although deep-vein thrombosis is the most common etiology, a nonthrombotic pulmonary embolism is not uncommon.

PATIENT CONCERNS

A 45-year-old woman was admitted to our hospital for progressive effort dyspnea for 3 weeks.

DIAGNOSIS

Echocardiography revealed a mobile mass extending from the right atrium to the bilateral proximal pulmonary artery. As the mass was no response to thrombotic therapy, intravenous leiomyomatosis was suspected. Computed tomography (CT) revealed a hypo-attenuated tumor extending from the ovarian vein to the pulmonary artery.

INTERVENTIONS

A 1-stage operation for the surgical removal of the tumor, right salpingo-oophorectomy and subtotal hysterectomy were performed. Surgical specimen was identified as uterine leiomyomatosis without malignant transformation.

OUTCOMES

The patient was followed- up for 2 years and subsequent CT did not reveal any notable lesions.

LESSONS

Nonthrombotic pulmonary embolism is a potentially life-threatening complication. This case indicated intravenous leiomyomatosis should be considered in the differential diagnosis for certain cases. Complete surgical excision was the only curative treatment.

摘要

理论依据

肺栓塞是一种潜在的严重疾病。虽然深静脉血栓形成是最常见的病因,但非血栓性肺栓塞也并不罕见。

患者情况

一名45岁女性因进行性劳力性呼吸困难3周入院。

诊断

超声心动图显示一个可移动的肿块从右心房延伸至双侧近端肺动脉。由于该肿块对血栓治疗无反应,怀疑为静脉内平滑肌瘤病。计算机断层扫描(CT)显示一个低密度肿瘤从卵巢静脉延伸至肺动脉。

干预措施

进行了一期手术,切除肿瘤、右侧输卵管卵巢切除术和子宫次全切除术。手术标本被确定为未发生恶变的子宫平滑肌瘤病。

结果

对患者进行了2年随访,后续CT未发现任何明显病变。

经验教训

非血栓性肺栓塞是一种潜在的危及生命的并发症。该病例表明,在某些病例的鉴别诊断中应考虑静脉内平滑肌瘤病。完整的手术切除是唯一的治愈性治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bdd/6370129/2212308e3d61/medi-98-e14118-g001.jpg

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