Brain Mind Institute, School of Life Sciences, École Polytechnique Fédérale Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Brain Mind Institute, School of Life Sciences, École Polytechnique Fédérale Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
Neuron. 2019 Jan 16;101(2):198-200. doi: 10.1016/j.neuron.2018.12.033.
Engram cells can encode and switch between multiple mnemonic functions, but how they intrinsically do so is unknown. Pignatelli, Ryan, and colleagues show that upon memory recall, the engram's excitability is transiently elevated, allowing its bearer to adapt to changing environments.
记忆印痕细胞可以编码并在多种记忆功能之间切换,但它们内在如何做到这一点尚不清楚。Pignatelli、Ryan 和同事们表明,在记忆回忆时,记忆印痕的兴奋性会短暂升高,使其承载者能够适应不断变化的环境。