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Complexities in analyzing human basophil responses to autoantibodies to IgE or FcεRI.

作者信息

Galli Stephen J

机构信息

Department of Pathology, Stanford University School of Medicine, Stanford, Calif; Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif; Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, Calif.

出版信息

J Allergy Clin Immunol. 2019 Mar;143(3):932-934. doi: 10.1016/j.jaci.2018.12.998. Epub 2019 Jan 14.

DOI:10.1016/j.jaci.2018.12.998
PMID:30654052
Abstract
摘要

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IgG Autoantibodies Against IgE from Atopic Dermatitis Can Induce the Release of Cytokines and Proinflammatory Mediators from Basophils and Mast Cells.特应性皮炎患者 IgG 自身抗体可诱导嗜碱性粒细胞和肥大细胞释放细胞因子和促炎介质。
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