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软膏性假性唇炎:一种有别于人为性唇炎的疾病。来自巴西圣保罗的 13 例患者系列研究。

Ointment Pseudo-Cheilitis: A Disease Distinct From Factitial Cheilitis. A Series of 13 Patients From São Paulo, Brazil.

机构信息

1 Department of Dermatology, Medical School, University of São Paulo, Brazil.

2 Department of Psychiatry, Medical School, University of São Paulo, Brazil.

出版信息

J Cutan Med Surg. 2019 May/Jun;23(3):277-281. doi: 10.1177/1203475418825112. Epub 2019 Jan 17.

DOI:10.1177/1203475418825112
PMID:30654637
Abstract

BACKGROUND

The terms exfoliative cheilitis, factitial cheilitis, and morsicatio labiorum are used to describe self-inflicted lesions of the lip.

OBJECTIVE

Here we report and analyze clinical, pathological, and therapeutic data on 13 patients with a form of factitial cheilitis that we believe should be considered a separate entity.

RESULTS

Eight patients were male and 5 patients were female. All patients reported pain and presented with crusts consisting of dried saliva and topical medications adherent to the surface of the lips. These patients expressed great concern with their condition, and reported several previous, ineffective treatments. Simple reassurance only was not effective; saline compresses alleviated symptoms for a few patients. Most patients were lost to follow-up. Biopsies were not performed on all patients.

CONCLUSION

This particular type of cheilitis artefacta has been previously described, but some features described herein are new and allow a specific approach: patient's behavior, the "protrusion sign," and possible improvement with antidepressants. For these cases, we propose the term ointment pseudo-cheilitis because it comprises the nature of the attached material and the lack of true inflammation. Further psychiatric characterization is a logical next step in further characterizing this difficult-to-treat condition.

摘要

背景

剥脱性唇炎、人为性唇炎和习惯性咬唇等术语用于描述唇部的自伤性病变。

目的

本研究报告并分析了 13 例我们认为应视为一种独立实体的人为性唇炎患者的临床、病理和治疗资料。

结果

8 例为男性,5 例为女性。所有患者均诉唇部疼痛,并出现由干燥唾液和附着于唇部表面的局部用药组成的结痂。这些患者对自己的病情非常关注,并报告了多次先前无效的治疗。单纯的安慰并不有效;生理盐水湿敷可缓解少数患者的症状。大多数患者失访。并非所有患者都进行了活检。

结论

这种特殊类型的人工性唇炎以前已有描述,但本文描述的一些特征是新的,可采用特定的方法:患者的行为、“突出征”以及可能通过抗抑郁药改善。对于这些病例,我们提出软膏性假性唇炎这一术语,因为它包含了附着物质的性质和缺乏真正炎症这两个方面。对这些病例进行进一步的精神疾病特征分析是进一步阐明这种难以治疗的疾病的合理下一步。

相似文献

1
Ointment Pseudo-Cheilitis: A Disease Distinct From Factitial Cheilitis. A Series of 13 Patients From São Paulo, Brazil.软膏性假性唇炎:一种有别于人为性唇炎的疾病。来自巴西圣保罗的 13 例患者系列研究。
J Cutan Med Surg. 2019 May/Jun;23(3):277-281. doi: 10.1177/1203475418825112. Epub 2019 Jan 17.
2
Factitial cheilitis in an adolescent.青少年人为性皮炎。 (注:这里不太准确,原文“Factitial cheilitis”准确意思是人为性唇炎,“Factitial dermatitis”才是人为性皮炎,可能原文有误,但按照要求翻译如上)
Pediatr Dermatol. 1999 Jan-Feb;16(1):12-5. doi: 10.1046/j.1525-1470.1999.99003.x.
3
Histopathologic findings in ointment pseudo-cheilitis: An alert to dermatopathologists.软膏性假唇炎的组织病理学表现:给皮肤病理学家的警示
J Cutan Pathol. 2024 Jan;51(1):53-57. doi: 10.1111/cup.14534. Epub 2023 Sep 5.
4
[Factitious crusting cheilitis].[人工性结痂性唇炎]
Ann Dermatol Venereol. 1984;111(11):1007-11.
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Exfoliative Cheilitis as a Manifestation of Factitial Cheilitis.剥脱性唇炎作为人工性唇炎的一种表现形式。
Cureus. 2018 May 2;10(5):e2565. doi: 10.7759/cureus.2565.
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Factitious cheilitis.人工性唇炎
J Am Acad Dermatol. 1983 Mar;8(3):368-72. doi: 10.1016/s0190-9622(83)70041-1.
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Factitious lip crusting.人为性唇结痂
Arch Dermatol. 1981 Jun;117(6):338-40.
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Exfoliative cheilitis--a factitious disorder?剥脱性唇炎——一种人为性疾病?
Int J Oral Maxillofac Surg. 1986 Jun;15(3):313-7. doi: 10.1016/s0300-9785(86)80091-6.
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Dermatitis artefacta.人工皮炎
Clin Dermatol. 2018 Nov-Dec;36(6):719-722. doi: 10.1016/j.clindermatol.2018.08.003. Epub 2018 Aug 16.
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Exfoliative cheilitis related to psychologic factors uncovered during primary immunodeficiency evaluation.原发性免疫缺陷评估过程中发现与心理因素相关的剥脱性唇炎。
Dermatol Online J. 2021 Jun 15;27(6). doi: 10.5070/D327654067.

引用本文的文献

1
Factitious cheilitis presenting as exfoliative cheilitis: A rare case report.表现为剥脱性唇炎的人工性唇炎:一例罕见病例报告。
Indian J Psychiatry. 2024 May;66(5):477-480. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_574_22. Epub 2024 May 20.
2
Artifactual pseudo-cheilitis: A case series of an underreported condition.人为性假性唇炎:一组未得到充分报道病症的病例系列
JAAD Case Rep. 2021 Sep 28;17:111-115. doi: 10.1016/j.jdcr.2021.09.012. eCollection 2021 Nov.