Department of Behavioural Sciences, Faculty of Public Health, University of Debrecen, Debrecen, Hungary.
Department of Behavioural Sciences, Faculty of Public Health, University of Debrecen, Debrecen, Hungary.
J Psychosom Res. 2019 Jan;116:6-9. doi: 10.1016/j.jpsychores.2018.11.001. Epub 2018 Nov 5.
To compare anxiety, depression, physical health and quality of life in patients with primary Raynaud's phenomenon (PRP) and patients with secondary Raynaud's phenomenon (SRP).
Adult patients with Raynaud's phenomenon (RP) were assessed for the severity of anxiety and depressive symptoms, physical health and quality of life by using the General Anxiety Disorder Scale (GAD-7), the Beck Depression Inventory (BDI), the 12-item Short Form Health Survey: Physical Component Scale (PCS-12), and the Raynaud Specific Quality of Life Questionnaire (RQLQ), respectively. Patients with PRP and SRP were recruited for comparison at a single clinical center in Debrecen, Hungary from September to December 2017.
In total, 60 primary and 41 secondary patients with RP were studied. Gender distribution, family status, employment status and smoking were similar in the two groups. Significantly more patients with SRP had anxiety and depressive symptoms than patients with PRP. Patients with SRP had significantly higher GAD-7 and BDI; and lower overall PCS-12 and RQLQ scores than patients with PRP.
Anxiety and depression is more common in patients with SRP than in patients with PRP. Patients with SRP have a lower physical health condition and RP specific quality of life than patients with PRP. Anxiety, depression and quality of life impairments should be taken into account when managing all patients with RP. Further study is needed to assess whether appropriately designed interventions have the potential to reduce the mental and physical health burdens of RP on quality of life (QOL), especially in patients with SRP.
比较原发性雷诺现象(PRP)和继发性雷诺现象(SRP)患者的焦虑、抑郁、身体健康和生活质量。
在 2017 年 9 月至 12 月期间,在匈牙利德布勒森的一个单一临床中心,对患有雷诺现象的成年患者进行了严重程度的焦虑和抑郁症状、身体健康和生活质量评估,分别使用一般焦虑障碍量表(GAD-7)、贝克抑郁量表(BDI)、12 项简明健康调查:生理成分量表(PCS-12)和雷诺特定生活质量问卷(RQLQ)。比较原发性和继发性 RP 患者。
共纳入 60 例原发性和 41 例继发性 RP 患者。两组患者的性别分布、家庭状况、就业状况和吸烟情况相似。与原发性 RP 患者相比,继发性 RP 患者的焦虑和抑郁症状明显更多。继发性 RP 患者的 GAD-7 和 BDI 评分明显更高,而原发性 RP 患者的总体 PCS-12 和 RQLQ 评分明显更低。
与原发性 RP 患者相比,继发性 RP 患者的焦虑和抑郁更为常见。继发性 RP 患者的身体健康状况和 RP 特异性生活质量低于原发性 RP 患者。在管理所有 RP 患者时,应考虑到焦虑、抑郁和生活质量受损的情况。需要进一步研究评估,设计恰当的干预措施是否有可能减轻 RP 对身体健康和生活质量的影响,特别是在继发性 RP 患者中。