Padilla Cristina, Katikineni Veena, Park Yongseok, Freno Leigh, Laffoon Maureen, Reichbaum Lee, Lafyatis Robert, Domsic Robyn
University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh Medical Center Arthritis and Autoimmunity Center, Pittsburgh, Pennsylvania.
ACR Open Rheumatol. 2025 Aug;7(8):e70074. doi: 10.1002/acr2.70074.
To assess the physical, emotional, and mental impact of regular audio-guided imagery (AGI) in patients with connective tissue disease (CTD)-associated Raynaud phenomenon (RP).
Sixteen adult patients with CTD-associated RP were enrolled in an open-label, single-arm, eight-week intervention with daily AGI at a single center. Patients completed surveys, including assessment of RP severity, depression/anxiety, and quality of life at baseline and the end of eight weeks.
Study participants demonstrated significant improvement in all patient reported outcomes, except Generalized Anxiety Disorder 7, which showed improvement but was not statistically significant. This eight-week intervention shows that patients with CTD-associated RP had less severe RP episodes, as well as improved quality of life and depressive symptoms.
AGI significantly improved several domains of health, including physical, emotional, and mental, in patients with CTD-associated RP who otherwise more commonly struggle with more RP attacks, lower quality of life, and depression. AGI is a low-cost, low-risk, and convenient therapy for CTD-associated RP. A larger study studying the effects of this intervention is indicated.
评估定期音频引导式想象(AGI)对结缔组织病(CTD)相关雷诺现象(RP)患者身体、情绪和心理的影响。
16名成年CTD相关RP患者在单一中心参加了一项开放标签、单臂、为期8周的干预,每天进行AGI。患者在基线和8周结束时完成了调查,包括RP严重程度、抑郁/焦虑和生活质量评估。
研究参与者在所有患者报告的结局方面均有显著改善,但广泛性焦虑障碍量表7除外,该量表虽有改善但无统计学意义。这项为期8周的干预表明,CTD相关RP患者的RP发作不那么严重,生活质量和抑郁症状也有所改善。
AGI显著改善了CTD相关RP患者的多个健康领域,包括身体、情绪和心理方面,这些患者通常更容易出现更多的RP发作、较低的生活质量和抑郁。AGI是一种针对CTD相关RP的低成本、低风险且方便的治疗方法。需要开展一项更大规模的研究来探究这种干预措施的效果。