缓释维拉帕米和长效普萘洛尔：治疗轻至中度高血压的疗效及副作用比较
Verapamil SR and propranolol LA: a comparison of efficacy and side effects in the treatment of mild to moderate hypertension.
作者信息
Bochsler J A, Simmons R L, Ward P J, Chester P C, Latham A N
机构信息
The Surgery, Bexley, Kent, UK.
出版信息
J Hum Hypertens. 1988 Mar;1(4):305-10.
PMID:3065507
Abstract
The efficacy, safety and toleration of sustained release verapamil (Securon SR, Knoll) and long acting propranolol (Inderal LA, ICI) in the treatment of mild to moderate hypertension were compared in a randomized, double-blind, parallel group study. Both drugs were of similar efficacy and were well tolerated in the majority of patients. However, in the verapamil SR treated group side-effects resulted in significantly fewer drug-related withdrawals.
摘要
在一项随机、双盲、平行组研究中，比较了缓释维拉帕米（Securon SR，诺尔公司）和长效普萘洛尔（心得安长效制剂，帝国化学工业公司）治疗轻至中度高血压的疗效、安全性和耐受性。两种药物疗效相似，大多数患者耐受性良好。然而，在维拉帕米SR治疗组中，副作用导致与药物相关的停药显著减少。
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引用本文的文献
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Verapamil. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.维拉帕米。对其药效学和药代动力学特性以及在高血压治疗中的应用的最新综述。
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