狒狒中跨越主要血型屏障的心脏同种异体移植。
Cardiac allotransplantation across major blood group barriers in the baboon.
作者信息
Cooper D K, Lexer G, Rose A G, Keraan M, Rees J, Du Toit E, Oriol R
机构信息
Department of Cardiothoracic Surgery, University of Cape Town Medical School Republic of South Africa.
出版信息
J Med Primatol. 1988;17(6):333-46.
In heterotopic heart transplantation experiments in Chacma baboons, some of the animals were significantly immunosuppressed with cyclosporine, resulting in prolonged cardiac allograft survival. ABO blood group incompatibility between recipient and donor did not significantly influence mean allograft survival, but early hyperacute (vascular) or acute (cellular) rejection occurred only when ABO incompatibility was present.
在南非大狒狒的异位心脏移植实验中，一些动物用环孢素进行了显著的免疫抑制，从而延长了心脏同种异体移植的存活时间。受体与供体之间的ABO血型不相容性并未显著影响同种异体移植的平均存活时间，但只有在存在ABO不相容性时才会发生早期超急性（血管性）或急性（细胞性）排斥反应。
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