From the Department of Radiology, Mayo Clinic, Rochester, Minnesota.
AJNR Am J Neuroradiol. 2019 Feb;40(2):376-381. doi: 10.3174/ajnr.A5934. Epub 2019 Jan 17.
The significance of renal contrast on CT myelography is uncertain. This project examined different patient populations undergoing CT myelography for the presence of renal contrast to determine whether this finding is of diagnostic value in spontaneous intracranial hypotension.
Four groups of patients were analyzed for renal contrast on CT myelography. The control group underwent CT myelography for reasons other than spontaneous intracranial hypotension ( = 47). Patients in study group 1 had spontaneous intracranial hypotension but CT myelography negative for dural CSF leak and CSF venous fistula ( = 83). Patients in study group 2 had spontaneous intracranial hypotension and CT myelography positive for dural CSF leak ( = 44). Patients in study group 3 had spontaneous intracranial hypotension and CT myelography suggestive of CSF venous fistula due to a hyperdense paraspinal vein ( = 17, eleven surgically confirmed).
Renal contrast was present on the initial CT myelography in 0/47 patients in the control group, 10/83 patients in group one, 1/44 patients in group 2, and 7/17 patients in group 3. Renal contrast on initial CT myelography in patients with suspected or surgically confirmed CSF venous fistula was significantly more likely than in patients with a dural CSF leak ( = .0003).
Renal contrast on initial CT myelography was seen only in patients with spontaneous intracranial hypotension. This was more common in confirmed/suspected CSF venous fistulas compared with dural leaks. Early renal contrast in patients with spontaneous intracranial hypotension should prompt scrutiny for a hyperdense paraspinal vein, and, if none is found, potentially advanced diagnostic studies.
CT 脊髓造影中肾对比的意义尚不确定。本项目检查了不同的 CT 脊髓造影患者群体中肾对比的存在情况,以确定该发现是否对自发性颅内低血压具有诊断价值。
对 CT 脊髓造影中肾对比的 4 组患者进行分析。对照组因自发性颅内低血压以外的原因接受 CT 脊髓造影(=47)。研究组 1 的患者自发性颅内低血压,但 CT 脊髓造影阴性,无硬脑膜 CSF 漏和 CSF 静脉瘘(=83)。研究组 2 的患者自发性颅内低血压,CT 脊髓造影阳性,有硬脑膜 CSF 漏(=44)。研究组 3 的患者自发性颅内低血压,CT 脊髓造影提示因脊柱旁静脉高密度而有 CSF 静脉瘘(=17,其中 11 例经手术证实)。
对照组 47 例患者中,初始 CT 脊髓造影未见肾对比;研究组 1 83 例患者中,有 10 例;研究组 2 44 例患者中,有 1 例;研究组 3 17 例患者中,有 7 例。疑似或经手术证实 CSF 静脉瘘患者的初始 CT 脊髓造影中肾对比明显多于硬脑膜 CSF 漏患者(=0.0003)。
初始 CT 脊髓造影中仅在自发性颅内低血压患者中观察到肾对比。在证实/疑似 CSF 静脉瘘患者中比硬脑膜漏患者更常见。自发性颅内低血压患者的早期肾对比应促使仔细检查脊柱旁高密度静脉,如果未发现,则可能需要进行更高级的诊断研究。