Introduction Obstructive lung disease, if not managed appropriately and in a timely manner, increases morbidity and mortality. The aim of this study was to see an obstruction on spirometry reports of clinically asymptomatic oil and gas field workers. Methods In this retrospective observational study, spirometry reports performed at the pulmonary function laboratory of Ziauddin Hospital and University, Karachi, were reviewed. All reports were of the clinically asymptomatic employees of an oil and gas company in Pakistan, who presented for their routine assessment. Obstructive impairment was defined as a forced expiratory volume in one second (FEV1) to forced vital capacity (FVC) ratio of less than 0.7. Results Of the total of 199 spirometry reports, 197 (99%) were of male employees. The mean age of the employees was 30.52 ± 8.24 years and 46 (23.1%) employee were smokers. Obstruction was observed in 48 (24.1%) of the reports of the employees with 13 (27.1%) smokers and 35 (72.9%) non-smokers. No statistically significant association between obstruction and gender, age, and smoking was observed. Conclusion In this study, we observed obstructive impairment in around one-fourth of the otherwise clinically asymptomatic oil and gas field workers with no apparent impact of baseline smoking behavior.