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采用切开法治疗纵隔子宫的宫腔镜子宫成形术是不良产科结局的危险因素吗?

Is hysteroscopic metroplasty using the incision method for septate uterus a risk factor for adverse obstetric outcomes?

作者信息

Ono Shuichi, Kuwabara Yoshimitsu, Matsuda Shigeru, Yonezawa Mirei, Watanabe Kenichiro, Akira Shigeo, Takeshita Toshiyuki

机构信息

Department of Obstetrics and Gynecology, Nippon Medical School Hospital, Tokyo, Japan.

出版信息

J Obstet Gynaecol Res. 2019 Mar;45(3):634-639. doi: 10.1111/jog.13884. Epub 2019 Jan 17.

Abstract

AIM

This study aimed to assess whether hysteroscopic metroplasty using the incision method for septate uterus is a risk factor for adverse obstetric outcomes during pregnancy or delivery.

METHODS

This retrospective, single-center cohort study of obstetric complications included 41 patients with recurrent pregnancy loss or unexplained infertility who underwent hysteroscopic metroplasty using the incision method for septate uterus. As controls, we recruited 1139 women who delivered at our hospital during the same period. The primary outcomes were mean weeks of delivery, mean birthweight, rate of cesarean section, rate of breech presentation, rate of post-partum hemorrhage, rate of preterm delivery, rate of placental abruption, rate of placenta previa, rate of placenta accreta and uterine rupture during pregnancy and delivery.

RESULTS

The two groups did not differ in terms of age, mean weeks of delivery, mean birthweight, rate of post-partum hemorrhage, rate of preterm delivery, rate of placental abruption, rate of placenta previa or rate of placenta accreta. The rates of cesarean section and breech presentation were significantly higher in the study group than in the control group (56.1 vs 27.7%; P = 0.0002 and 19.5 vs 6.8%; P = 0.007, respectively). There were no cases of uterine rupture during pregnancy or delivery following hysteroscopic metroplasty.

CONCLUSION

Hysteroscopic metroplasty using the incision method for septate uterus is not a risk factor for adverse obstetric outcomes. No severe complications, such as placenta abruption, placenta previa, placenta accreta, uterine rupture or heavy hemorrhage, were observed in the postoperative live birth group.

摘要

目的

本研究旨在评估采用切开法治疗纵隔子宫的宫腔镜子宫成形术是否为妊娠或分娩期间不良产科结局的危险因素。

方法

这项关于产科并发症的回顾性单中心队列研究纳入了41例因复发性流产或不明原因不孕而接受采用切开法治疗纵隔子宫的宫腔镜子宫成形术的患者。作为对照,我们招募了同期在我院分娩的1139名女性。主要结局指标包括平均分娩孕周、平均出生体重、剖宫产率、臀位分娩率、产后出血率、早产率、胎盘早剥率、前置胎盘率、胎盘植入率以及妊娠和分娩期间的子宫破裂情况。

结果

两组在年龄、平均分娩孕周、平均出生体重、产后出血率、早产率、胎盘早剥率、前置胎盘率或胎盘植入率方面无差异。研究组的剖宫产率和臀位分娩率显著高于对照组(分别为56.1%对27.7%;P = 0.0002以及19.5%对6.8%;P = 0.007)。宫腔镜子宫成形术后妊娠或分娩期间未发生子宫破裂病例。

结论

采用切开法治疗纵隔子宫的宫腔镜子宫成形术并非不良产科结局的危险因素。在术后活产组中未观察到胎盘早剥、前置胎盘、胎盘植入、子宫破裂或大出血等严重并发症。

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