Gkentzi Despoina, Dimitriou Gabriel
Department of Paediatrics, Patras Medical School, Patras, Greece.
Curr Pediatr Rev. 2019;15(1):47-52. doi: 10.2174/1573396315666190118101953.
Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly prescribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inappropriately with various short and long-term effects. The rational use of antimicrobials is of paramount importance in this population and structured antimicrobial stewardship interventions should be in place. These interventions are slightly different from those used in adults and older children due to the particularities of the neonatal medicine. The aim of this review is to provide an update in the field and identify areas for further consideration and future research.
新生儿是易受感染的群体，新生儿败血症是全球范围内死亡和发病的主要原因。因此，抗菌药物是新生儿重症监护病房最常用的处方药物，但不幸的是，它们经常被不恰当地使用，并产生各种短期和长期影响。合理使用抗菌药物在这一人群中至关重要，应实施结构化的抗菌药物管理干预措施。由于新生儿医学的特殊性，这些干预措施与成人和大龄儿童使用的措施略有不同。本综述的目的是提供该领域的最新情况，并确定需要进一步考虑和未来研究的领域。
