使用荧光核仁肽传感器对 ATP 和 ADP 进行高选择性双重感应。
Highly selective dual sensing of ATP and ADP using fluorescent ribonucleopeptide sensors.
机构信息
Institute of Advanced Energy, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan.
出版信息
Chem Commun (Camb). 2019 Jan 31;55(11):1611-1614. doi: 10.1039/c8cc09934k.
PMID:30657140
Abstract
Highly selective fluorescent sensors for ATP and ADP were constructed from RNA aptamers by applying a modular design of a ribonucleopeptide scaffold. These sensors allow facile and quantitative detection of ATP and ADP simultaneously in a solution and enable monitoring of the time-course changes of ATP and ADP concentrations in an enzymatic reaction.
摘要
通过应用核酶肽支架的模块化设计，从 RNA 适体构建了对 ATP 和 ADP 具有高选择性的荧光传感器。这些传感器可在溶液中方便且定量地同时检测 ATP 和 ADP，并能够监测酶反应中 ATP 和 ADP 浓度的时程变化。
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