Walker Robrina, Northrup Thomas F, Tillitski John, Bernstein Ira, Greer Tracy L, Trivedi Madhukar H
a Department of Psychiatry , University of Texas Southwestern Medical Center , Dallas , Texas , USA.
b Department of Family and Community Medicine , The University of Texas Health Science Center at Houston, McGovern Medical School , Houston , Texas , USA.
Subst Use Misuse. 2019;54(3):351-361. doi: 10.1080/10826084.2018.1467453. Epub 2019 Jan 18.
Cocaine and methamphetamine have similar withdrawal symptoms and many individuals concurrently use both substances; however, no measures concurrently assess withdrawal from multiple stimulants.
This study's aim was to explore the Stimulant Selective Severity Assessment (SSSA), a modified version of the Cocaine Selective Severity Assessment (CSSA), in a sample of stimulant users to determine if it can assess withdrawal symptoms in users of one or more stimulants.
Baseline data were analyzed from the STimulant Reduction Intervention using Dosed Exercise trial, a multisite randomized clinical trial that evaluated exercise versus health education on drug use outcomes in individuals with stimulant use disorders. Data were analyzed for internal consistency, construct validity, and scale dimensionality.
Internal consistency for the full sample was good (α = 0.81; N = 302), with similar alphas in Cocaine (0.81; n = 177) and Cocaine/Other Stimulant (0.82; n = 92) groups, but with much lower alpha for the group without cocaine use (Other Stimulant, i.e., primarily methamphetamine, α = 0.66; n = 32). Support for construct validity was evidenced by significant positive correlations (r = 0.17 to 0.67) with measures of stimulant craving, depressive symptoms, and pain. Four factors were revealed. Conclusions/Importance: The Stimulant Selective Severity Assessment is a new measure that can be used to assess withdrawal symptoms in users of cocaine or cocaine plus methamphetamine, but it should not be administered to users of methamphetamine only.
可卡因和甲基苯丙胺有相似的戒断症状,许多人同时使用这两种物质;然而,尚无措施能同时评估多种兴奋剂的戒断情况。
本研究旨在对一组兴奋剂使用者样本探索兴奋剂选择性严重程度评估(SSSA),这是可卡因选择性严重程度评估(CSSA)的改良版本,以确定它是否能评估一种或多种兴奋剂使用者的戒断症状。
对使用定量运动进行兴奋剂减量干预试验的基线数据进行分析,该试验是一项多中心随机临床试验,评估运动与健康教育对兴奋剂使用障碍个体药物使用结果的影响。对数据进行内部一致性、结构效度和量表维度分析。
全样本的内部一致性良好(α = 0.81;N = 302),可卡因组(0.81;n = 177)和可卡因/其他兴奋剂组(0.82;n = 92)的α值相似,但未使用可卡因的组(其他兴奋剂组,即主要是甲基苯丙胺,α = 0.66;n = 32)的α值低得多。与兴奋剂渴望、抑郁症状和疼痛测量指标的显著正相关(r = 0.17至0.67)证明了对结构效度的支持。揭示了四个因素。结论/重要性:兴奋剂选择性严重程度评估是一种可用于评估可卡因使用者或可卡因加甲基苯丙胺使用者戒断症状的新措施,但不应仅用于甲基苯丙胺使用者。