Department for Infectious Disease Epidemiology, Division for HIV/AIDS, STI and Blood-borne Infections, Robert Koch Institute, Berlin, Germany.
Department for Infectious Disease Epidemiology, Division for HIV/AIDS, STI and Blood-borne Infections, Robert Koch Institute, Berlin, Germany; Charité University of Medicine, Berlin, Germany.
Int J Infect Dis. 2019 Apr;81:100-106. doi: 10.1016/j.ijid.2019.01.015. Epub 2019 Jan 15.
The aim of this study was to investigate the association between detention experience and hepatitis C virus (HCV) status, the role of duration and frequency of detention, and whether risk behaviours practiced in detention could explain an observed increase in risk.
Current drug injectors (injecting in the last 12 months) were recruited to participate in a sero-behavioural, cross-sectional survey using respondent-driven sampling in eight German cities during the years 2011-2014. Using multivariable logistic regression, the association between HCV status and reported detention experience was investigated.
A total of 1998 participants were included in the analysis. Of these, 19.9% reported no detention experience, 28.6% short and rare experience (≤3.5 years in total, ≤3 times), 12.1% short but frequent experience, 7.1% long but rare experience, and 32.4% long and frequent experience. After correcting for HCV risk factors, the association between detention experience and HCV status remained statistically significant. By adjusting the model for intramural risk behaviours, the odds ratios of detention experience were reduced but remained significant.
The proportion of people who inject drugs positive for HCV increased with both frequency and duration of their detention experience. As intramural risk behaviours could not fully explain this increase, it appears that transfers between community and custody may confer additional risks.
本研究旨在调查被拘留经历与丙型肝炎病毒（HCV）状态之间的关联，探讨拘留时间和频率的作用，以及被拘留期间的危险行为是否可以解释观察到的风险增加。
2011 年至 2014 年期间，我们使用基于受访者驱动抽样（RDS）的方法，在德国八个城市招募了目前使用毒品的注射者（在过去 12 个月内注射过毒品）参与这项血清学和行为学的横断面调查。我们使用多变量逻辑回归，调查了 HCV 状态与报告的拘留经历之间的关联。
共有 1998 名参与者被纳入分析。其中，19.9%的人没有拘留经历，28.6%的人有短期且罕见的拘留经历（总拘留时间≤3.5 年，≤3 次），12.1%的人有短期但频繁的拘留经历，7.1%的人有长期但罕见的拘留经历，32.4%的人有长期且频繁的拘留经历。在纠正 HCV 风险因素后，拘留经历与 HCV 状态之间的关联仍然具有统计学意义。通过将模型调整为监狱内的风险行为，拘留经历的优势比虽然降低，但仍然显著。
HCV 阳性的注射毒品者比例随着拘留经历的频率和时间的增加而增加。由于监狱内的风险行为不能完全解释这种增加，因此社区和拘留所之间的转移似乎会带来额外的风险。
