Chen Zhongyi, Deblois Simon, Toporowicz Kevin, Boldeanu Irina, Francoeur Marie-Odile, Sadouni Manel, Lepanto Luigi, Chartrand-Lefebvre Carl
Department of Radiology, Centre Hospitalier de l'Université de Montréal (CHUM), 1051 Sanguinet Street, Montréal, QC, H2X 0C1, Canada.
Health Technology Assessment Unit, CHUM, Montréal, QC, Canada.
BMC Res Notes. 2019 Jan 18;12(1):41. doi: 10.1186/s13104-019-4076-8.
To assess computed tomography pulmonary angiography (CTPA) positive yield rate for pulmonary embolism (PE) in a Canadian academic tertiary center.
This one-center retrospective cross-sectional study includes from 5565 (model 1) to 5296 (model 2) patients that were evaluated for suspected PE in 2015, among which 1331 (23.9% (model 1) to 25.1% (model 2)) underwent CTPA. Mean age of CTPA patients was 60.2 ± 16.6 years, of which 575 were males (43.2%). Two hundred eleven CTPA examinations were positive for PE, giving a CTPA positive yield rate of 15.9% (95% CI (13.93-17.87)). One hundred and thirteen (8.1%) CTPA were considered indeterminate, and eleven were considered nondiagnostic (0.8%). Among the 211 CTPA positive for PE, 67 (32%) were proximal emboli, 98 (47%) were segmental emboli and 44 (21%%) were subsegmental emboli. In conclusion, in this retrospective study done in a Canadian academic tertiary center, we report a positive rate of 15.9% for PE detection with CTPA, which is above the generally accepted lower threshold of 10% for the yield of CTPA.
评估加拿大一家学术性三级医疗中心计算机断层扫描肺动脉造影（CTPA）对肺栓塞（PE）的阳性检出率。
这项单中心回顾性横断面研究纳入了2015年因疑似PE接受评估的5565例（模型1）至5296例（模型2）患者，其中1331例（23.9%（模型1）至25.1%（模型2））接受了CTPA检查。接受CTPA检查患者的平均年龄为60.2±16.6岁，其中575例为男性（43.2%）。211例CTPA检查结果为PE阳性，CTPA阳性检出率为15.9%（95%CI（13.93 - 17.87））。113例（8.1%）CTPA结果被认为不确定，11例被认为无法诊断（0.8%）。在211例CTPA结果为PE阳性的患者中，67例（32%）为近端栓塞，98例（47%）为节段性栓塞，44例（21%）为亚段性栓塞。总之，在这家加拿大学术性三级医疗中心进行的这项回顾性研究中，我们报告CTPA对PE的检测阳性率为15.9%，高于CTPA通常公认的10%的较低阳性率阈值。
