Belcaro G, Laurora G, Ricci A, Cianchetti E, Legnini M, Napolitano A M
Cardiovascular Clinic, Chieti University, Italy.
Acta Chir Belg. 1988 Sep-Oct;88(5):323-7.
Evaluation of flow in nodular tumors of the breast may be performed by Doppler and computerized frequency analysis. In 46 nodules of the breast (22 malignant) the nodular flow velocity and frequency analysis revealed a faster flow with a significantly higher peak frequency and mean velocity. The intensity of sound which may be considered an index of the entity of flow in the nodule was larger than that observed in the normal surrounding breast tissue. In malignant nodules and generally in fast growing nodules the flow velocity and intensity was even larger. The flow intensity and velocity was also well correlated with the growth rate as reported by single patients. In elder patients a slow rate of growth even in tumors of larger size was associated with a significantly increased flow in comparison with the normal breast tissue but this increase was not particularly large when compared with fast growing nodules in younger subjects. In conclusion the evaluation of flow characteristics (mainly velocity, frequency analysis and intensity) may be a useful index of the growth rate of nodular tumors of the breast and these data may be useful to evaluate and monitor the evolution and pathophysiology of these nodules.
乳腺结节性肿瘤的血流评估可通过多普勒和计算机频率分析来进行。在46个乳腺结节（22个为恶性）中，结节血流速度和频率分析显示血流更快，峰值频率和平均速度显著更高。可被视为结节内血流实体指标的声音强度大于在周围正常乳腺组织中观察到的强度。在恶性结节以及一般生长迅速的结节中，血流速度和强度甚至更大。如个别患者报告所示，血流强度和速度也与生长速率密切相关。在老年患者中，即使肿瘤体积较大，生长速率缓慢，但与正常乳腺组织相比，血流仍显著增加，不过与年轻受试者中生长迅速的结节相比，这种增加并不特别大。总之，血流特征（主要是速度、频率分析和强度）的评估可能是乳腺结节性肿瘤生长速率的一个有用指标，这些数据可能有助于评估和监测这些结节的演变及病理生理学情况。
