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伴有鞍内延伸的成人鞍旁毛细血管瘤

Adult Parasellar Capillary Hemangioma with Intrasellar Extension.

作者信息

Low Jacob Chen Ming, Maratos Eleni, Kumar Atul, King Andrew, Al-Sarraj Safa, Barazi Sinan

机构信息

Department of Neurosurgery, King's College Hospital, London, United Kingdom.

Department of Neurosurgery, King's College Hospital, London, United Kingdom.

出版信息

World Neurosurg. 2019 Apr;124:184-191. doi: 10.1016/j.wneu.2018.12.185. Epub 2019 Jan 17.

DOI:10.1016/j.wneu.2018.12.185
PMID:30660877
Abstract

BACKGROUND

Capillary hemangiomata are benign vascular tumors that typically occur in children. They rarely occur in the central nervous system. Intracranial capillary hemangiomata in adults are very rare entities with only 18 cases reported in the literature. We report a case of parasellar capillary hemangiomata that extended into the sella in a 64-year-old woman as well as a review of the literature in adults.

CASE DESCRIPTION

We report a 64-year-old patient who presented with a headache, left-sided paresthesia, and weakness. Initial computed tomography of her brain showed a left-sided 3 cm × 2.5 cm parasellar lesion with intrasellar extension and no mass effect. Subsequent magnetic resonance imaging (MRI) showed a lesion that was homogenously hyperintense on T2-weighted MRI and fluid-attenuated inversion recovery, isointense with adjacent brain parenchyma on T1-weighted MRI, and which demonstrated enhancement after contrast administration. The patient initially underwent an endoscopic transsphenoidal biopsy, which was inconclusive, followed by a craniotomy, biopsy, and debulking. Histologic examination showed fibrous tissue containing numerous thin-walled and irregular vascular channels of varying sizes. There was a very mild associated inflammatory infiltrate, mainly formed of small mononuclear chronic inflammatory cells and occasional histiocytes. The histologic appearances were in keeping with capillary hemangiomata.

CONCLUSIONS

Capillary hemangiomata related to the sella are very rare and can easily be misdiagnosed on imaging alone. The present case highlights capillary hemangiomata as an important, albeit rare, differential when considering a sellar or parasellar mass.

摘要

背景

毛细血管瘤是一种良性血管肿瘤,通常发生于儿童。它们很少发生于中枢神经系统。成人颅内毛细血管瘤是非常罕见的实体,文献中仅报道过18例。我们报告一例64岁女性鞍旁毛细血管瘤延伸至鞍内的病例,并对成人病例的文献进行综述。

病例描述

我们报告一名64岁患者,其表现为头痛、左侧感觉异常和无力。她最初的脑部计算机断层扫描显示左侧鞍旁有一个3 cm×2.5 cm的病变,延伸至鞍内,无占位效应。随后的磁共振成像(MRI)显示,该病变在T2加权MRI和液体衰减反转恢复序列上呈均匀高信号,在T1加权MRI上与相邻脑实质等信号,增强扫描后有强化。患者最初接受了内镜经蝶窦活检,结果不明确,随后进行了开颅手术、活检和肿瘤切除。组织学检查显示纤维组织中含有许多大小不一的薄壁不规则血管通道。有非常轻微的相关炎性浸润,主要由小单核慢性炎性细胞和偶尔的组织细胞组成。组织学表现符合毛细血管瘤。

结论

与鞍区相关的毛细血管瘤非常罕见,仅靠影像学检查很容易误诊。本病例强调了毛细血管瘤在考虑鞍区或鞍旁肿块时作为一种重要的鉴别诊断,尽管很罕见。

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Case of a Pregnant Woman with Capillary Hemangioma of the Parasellar Region.一例患有鞍旁区域毛细血管瘤的孕妇病例。
NMC Case Rep J. 2022 Apr 21;9:77-82. doi: 10.2176/jns-nmc.2021-0326. eCollection 2022.
3
Capillary hemangioma of the sphenoid sinus with intrasellar and parasellar extensions.蝶窦毛细血管瘤伴鞍内及鞍旁扩展
Radiol Case Rep. 2021 Nov 10;17(1):156-160. doi: 10.1016/j.radcr.2021.10.011. eCollection 2022 Jan.
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Intracranial, Intra-parenchymal Capillary Hemangioma - Case Report.颅内脑实质内毛细血管瘤——病例报告
NMC Case Rep J. 2020 Mar 24;7(2):43-46. doi: 10.2176/nmccrj.cr.2019-0145. eCollection 2020 Apr.