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骨再生医学中电磁场应用的综合概述。

A comprehensive overview on utilizing electromagnetic fields in bone regenerative medicine.

作者信息

Azadian Esmaeel, Arjmand Bahar, Khodaii Zohreh, Ardeshirylajimi Abdolreza

机构信息

a Urogenital Stem Cell Research Center , Shahid Beheshti University of Medical Sciences , Tehran , Iran.

b Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine , Shahid Beheshti University of Medical Sciences , Tehran , Iran.

出版信息

Electromagn Biol Med. 2019;38(1):1-20. doi: 10.1080/15368378.2019.1567527. Epub 2019 Jan 19.


DOI:10.1080/15368378.2019.1567527
PMID:30661411
Abstract

Stem cells are one of the most important sources to develope  a new strategy for repairing bone lesions through tissue engineering. Osteogenic differentiation of stem cells can be affected by various factors such as biological, chemical, physiological, and physical ones. The application of ELF-EMFs has been the subject of many research in bone tissue engineering and evidence suggests that this exogenous physical stimulus can promote osteogenic differentiation in several types of  cells. The purpose of this paper is to review the current knowledge on the effects of EMFs on stem cells in bone tissue engineering studies. We recapitulated and analyzed 39 articles that were focused on the application of EMFs for bone tissue engineering purposes. We tabulated scattered information from these articles for easy use and tried to provide an overview of conducted research and identify the knowledge gaps in the field.

摘要

干细胞是通过组织工程开发修复骨缺损新策略的最重要来源之一。干细胞的成骨分化会受到多种因素的影响,如生物学、化学、生理学和物理因素。极低频电磁场(ELF-EMFs)的应用一直是骨组织工程中许多研究的主题,有证据表明这种外源性物理刺激可以促进几种类型细胞的成骨分化。本文的目的是综述骨组织工程研究中关于电磁场对干细胞影响的现有知识。我们总结并分析了39篇专注于将电磁场应用于骨组织工程目的的文章。我们将这些文章中分散的信息制成表格以便于使用,并试图概述已进行的研究并确定该领域的知识空白。

相似文献

[1]
A comprehensive overview on utilizing electromagnetic fields in bone regenerative medicine.

Electromagn Biol Med. 2019

[2]
Induced Pluripotent Stem Cells as a new Strategy for Osteogenesis and Bone Regeneration.

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[3]
Synergism of Electrospun Nanofibers and Pulsed Electromagnetic Field on Osteogenic Differentiation of Induced Pluripotent Stem Cells.

ASAIO J. 2018

[4]
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[5]
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[6]
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[7]
Electromagnetic fields and nanomagnetic particles increase the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells.

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[8]
The Role of Low-Frequency Electromagnetic Fields on Mesenchymal Stem Cells Differentiation: A Systematic Review.

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[9]
[Bone and Stem Cells. Advancement of regenerative medicine in the locomotive system using iPS cells].

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[10]
Osteogenic differentiation potential of mesenchymal stem cells cultured on nanofibrous scaffold improved in the presence of pulsed electromagnetic field.

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引用本文的文献

[1]
Complex Magnetic Fields: Harnessing the Electromagnetic Symphony for Possible Applications in Regenerative Medicine and Antifungal Properties.

Int Wound J. 2025-6

[2]
Impact of Extremely Low-Frequency Electromagnetic Fields on Skeletal Muscle of Sedentary Adult Mice: A Pilot Study.

Int J Mol Sci. 2024-9-12

[3]
Biophysical control of plasticity and patterning in regeneration and cancer.

Cell Mol Life Sci. 2023-12-15

[4]
Electromagnetic fields regulate calcium-mediated cell fate of stem cells: osteogenesis, chondrogenesis and apoptosis.

Stem Cell Res Ther. 2023-5-16

[5]
Possible Synergies of Nanomaterial-Assisted Tissue Regeneration in Plasma Medicine: Mechanisms and Safety Concerns.

Nanomaterials (Basel). 2022-9-28

[6]
The Role of Low-Frequency Electromagnetic Fields on Mesenchymal Stem Cells Differentiation: A Systematic Review.

Tissue Eng Regen Med. 2022-12

[7]
Osteogenic effect of electromagnetic fields on stem cells derived from rat bone marrow cultured in osteogenic medium versus conditioned medium in vitro.

Cell Tissue Bank. 2023-6

[8]
DNMT1 and miRNAs: possible epigenetics footprints in electromagnetic fields utilization in oncology.

Med Oncol. 2021-9-8

[9]
In Vitro Effect of Replicated Porous Polymeric Nano-MicroStructured Biointerfaces Characteristics on Macrophages Behavior.

Nanomaterials (Basel). 2021-7-25

[10]
Pulsed Electromagnetic Field Stimulation in Osteogenesis and Chondrogenesis: Signaling Pathways and Therapeutic Implications.

Int J Mol Sci. 2021-1-15

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