Morley A R
Department of Pathology, University of Newcastle upon Tyne, U.K.
APMIS Suppl. 1988;4:74-81.
Crescents are an important structure in many forms of glomerulonephritis and a major cause of destruction of the renal corpuscle. There has been considerable discussion of the cellular content of crescents and of the role of breaks in the glomerular capillary basement membranes. Less attention has been given to abnormalities of Bowman's capsule. We present 2 cases of anti-gbm nephritis showing unusual breaks in Bowman's capsule with a peri-hilar distribution. The mechanisms leading to the rupture of Bowman's capsule are reviewed, as are the possible effect of capsular ruptures on the crescentic cell content.
新月体是多种形式肾小球肾炎的重要结构,也是肾小体破坏的主要原因。关于新月体的细胞成分以及肾小球毛细血管基底膜破裂的作用,已经有了大量讨论。而对肾小囊异常的关注较少。我们报告2例抗肾小球基底膜肾炎病例,其肾小囊出现不寻常的破裂,且呈肾门周围分布。本文回顾了导致肾小囊破裂的机制,以及囊破裂对新月体细胞成分可能产生的影响。