Division of Operative Dentistry, Faculty of Dentistry, Thammasat University, Pathumthani, Thailand.
Divisions of Oral and Maxillofacial Pathology and Forensic Dentistry, Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, Thailand.
J Stomatol Oral Maxillofac Surg. 2019 Dec;120(6):591-594. doi: 10.1016/j.jormas.2019.01.006. Epub 2019 Jan 18.
Dental amalgam remains one of standard direct restorative materials for posterior teeth. However, direct contact of oral mucosa with this material can cause oral lichenoid lesion (OLL), albeit rare. It has been proposed that hypersensitivity reaction to mercury is responsible to the pathogenesis of OLL. In addition to clinical features and histopathological examination, allergic patch test and removing the suspected causal material are pivotal to the diagnosis. We reported a case of OLL associated with dental amalgam. The lesion subsided clinically after replacement of amalgam with resin composite material with no need of biopsy or pharmacological treatment. A concise review of clinico-pathological aspects and current recommendations on management of this disease was also presented.
银汞合金仍然是后牙的标准直接修复材料之一。然而,口腔黏膜与这种材料直接接触会引起口腔类天疱疮样病变(OLL),尽管很少见。据认为,对汞的过敏反应是 OLL 发病机制的原因。除了临床特征和组织病理学检查外,过敏斑贴试验和去除可疑的致病材料对诊断至关重要。我们报告了一例与银汞合金有关的 OLL。在使用树脂复合材料代替银汞合金后,病变在临床上消退,无需进行活检或药物治疗。还简要回顾了这种疾病的临床病理方面和当前的治疗建议。