通过体内蛋白质合成抑制和肾小管蛋白质重吸收抑制研究，证实无活性血浆肾素主要通过肾脏分泌和清除。
Evidence for a predominant renal secretion and clearance of inactive plasma renin, studied by in vivo inhibition of protein synthesis, and inhibition of renal tubular protein reabsorption.
作者信息
Nielsen A H, Hermann K L, Mazanti I, Poulsen K
机构信息
Institute of Biochemistry, Royal Dental College, Copenhagen N, Denmark.
出版信息
Clin Exp Hypertens A. 1988;10(6):1301-3. doi: 10.1080/07300077.1988.11878925.
Abstract
Inactive plasma renin is mainly secreted and eliminated by the kidneys in the mouse. The half-life of inactive plasma renin is 6 hours or less. The kidneys remove inactive renin from the circulation by glomerular ultrafiltration.
摘要
在小鼠中，无活性血浆肾素主要由肾脏分泌和清除。无活性血浆肾素的半衰期为6小时或更短。肾脏通过肾小球超滤从循环中清除无活性肾素。
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