G. V. (Sonny) Montgomery VA Medical Center, Jackson, MS, USA; University of Mississippi Medical Center, Jackson, MS, USA.
G. V. (Sonny) Montgomery VA Medical Center, Jackson, MS, USA.
J Subst Abuse Treat. 2019 Mar;98:9-14. doi: 10.1016/j.jsat.2018.11.008. Epub 2018 Nov 20.
Although central to the hepatitis C virus (HCV) epidemic, many patients with both substance use disorders (SUD) and HCV have difficultly engaging in treatment for either condition. To facilitate HCV care in Veterans with active SUD, a comprehensive HCV screening, education, referral, and treatment program was integrated into a VA residential SUD treatment program.
Evaluation of HCV screening, education, referral, and treatment initiative among admissions to a residential SUD treatment program from December 2014 to April 2018.
To date, 97.49% (582/597) of admissions to the program have been screened for HCV infection, with 12.71% (74/582) of the cases confirmed HCV-positive, and 100% (74/74) of the positive cases being connected or re-connected to the infectious disease clinic for further evaluation and, if appropriate, to begin HCV pharmacotherapy. Importantly, 18.92% (14/74) of the HCV-positive cases were newly diagnosed and would have likely gone undetected without this program. Of the HCV-positive cases, 78.38% (58/74) have received pharmacotherapy, with a sustained virologic response rate of 82.76% (48/58).
Integrating comprehensive HCV care within a residential SUD treatment program using a collaborative care model can substantially increase the detection of previously undiagnosed infections, facilitate linkage to care, and promote HCV treatment uptake among HCV-infected Veterans with SUD.
尽管物质使用障碍(SUD)和丙型肝炎病毒(HCV)患者是 HCV 流行的核心人群,但许多患者在接受这两种疾病的治疗时都存在困难。为了促进有活跃 SUD 的退伍军人接受 HCV 护理,我们将全面的 HCV 筛查、教育、转诊和治疗计划整合到退伍军人事务部的一个住院 SUD 治疗项目中。
评估 2014 年 12 月至 2018 年 4 月期间入住住院 SUD 治疗项目的患者的 HCV 筛查、教育、转诊和治疗情况。
迄今为止,该项目 97.49%(582/597)的入院患者接受了 HCV 感染筛查,其中 12.71%(74/582)的病例被确诊为 HCV 阳性,且 100%(74/74)的阳性病例均被转至传染病门诊进行进一步评估,如果合适,开始 HCV 药物治疗。重要的是,18.92%(14/74)的 HCV 阳性病例是新诊断的,如果没有该项目,这些病例很可能未被发现。在 HCV 阳性病例中,78.38%(58/74)接受了药物治疗,持续病毒学应答率为 82.76%(48/58)。
使用协作式护理模式将全面的 HCV 护理整合到住院 SUD 治疗项目中,可以显著提高对既往未诊断感染的检出率,促进与治疗的衔接,并促进有 SUD 的 HCV 感染退伍军人接受 HCV 治疗。