Gynecologic Oncology, Olive View-UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States of America.
Radiation Oncology, , Regional Health - John T. Vucurevich Cancer Care Institute, Rapid City, SD, United States of America.
Gynecol Oncol. 2019 Mar;152(3):540-547. doi: 10.1016/j.ygyno.2018.10.016. Epub 2019 Jan 18.
Brachytherapy is well-established as an integral component in the standard of care for treatment of patients receiving primary radiotherapy for cervical cancer. A decline in brachytherapy has been associated with negative impacts on survival in the era of modern EBRT techniques. Conformal external beam therapies such intensity modulated radiation therapy (IMRT) or stereotactic body radiation therapy (SBRT) should not be used as alternatives to brachytherapy in patients undergoing primary curative-intent radiation therapy for cervical cancer. Computed tomography or magnetic resonance image-guided adaptive brachytherapy is evolving as the preferred brachytherapy method. With careful care coordination EBRT and brachytherapy can be successfully delivered at different treatment centers without compromising treatment time and outcome in areas where access to brachytherapy maybe limited.
近距离放射治疗已被确立为宫颈癌患者接受根治性放疗标准治疗方案的一个组成部分。在现代调强放疗技术时代,近距离放射治疗的减少与生存的负面影响有关。调强适形放疗(IMRT)或立体定向体部放疗(SBRT)等适形外照射治疗不应作为宫颈癌根治性放疗患者的近距离放射治疗替代方法。计算机断层扫描或磁共振图像引导自适应近距离放射治疗正在发展成为首选的近距离放射治疗方法。通过精心的护理协调,在近距离放射治疗可能受限的地区,EBRT 和近距离放射治疗可以在不同的治疗中心成功进行,而不会影响治疗时间和结果。