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铱刀的物理和剂量学方面

Physical and Dosimetric Aspects of the Iridium-Knife.

作者信息

Roussakis Yiannis, Anagnostopoulos Georgios

机构信息

Department of Medical Physics, German Oncology Center, Limassol, Cyprus.

出版信息

Front Oncol. 2021 Nov 9;11:728452. doi: 10.3389/fonc.2021.728452. eCollection 2021.

DOI:10.3389/fonc.2021.728452
PMID:34858815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8630660/
Abstract

The three-dimensional iridium-192 (Ir) high-dose-rate (HDR) brachytherapy manifests itself as a high-precision, hypofractionated, dose-escalating, minimally invasive method in the armamentarium of contemporary radiation oncology clinical applications. In this study, the physical aspects of the Ir radionuclide are presented. Its dosimetric application in HDR brachytherapy for different anatomical sites (prostate, gynecological malignancies, liver, and intrathoracic tumors) as well as the corresponding dosimetric comparison with the stereotactic body radiation therapy (SBRT) techniques based on a representative selection of dosimetric publications is reviewed and illustrated.

摘要

三维铱-192（Ir）高剂量率（HDR）近距离放射治疗在当代放射肿瘤学临床应用手段中表现为一种高精度、低分割、剂量递增的微创方法。在本研究中，介绍了铱放射性核素的物理特性。基于剂量学出版物的代表性选择，综述并举例说明了其在不同解剖部位（前列腺、妇科恶性肿瘤、肝脏和胸内肿瘤）的HDR近距离放射治疗中的剂量学应用，以及与立体定向体部放射治疗（SBRT）技术的相应剂量学比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9e7/8630660/481e89a6d518/fonc-11-728452-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9e7/8630660/481e89a6d518/fonc-11-728452-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9e7/8630660/481e89a6d518/fonc-11-728452-g001.jpg

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本文引用的文献

1
Real-world dosimetric comparison between CyberKnife SBRT and HDR brachytherapy for the treatment of prostate cancer.CyberKnife SBRT 与 HDR 近距离放疗治疗前列腺癌的真实世界剂量学比较。
Brachytherapy. 2021 Jan-Feb;20(1):44-49. doi: 10.1016/j.brachy.2020.07.011. Epub 2020 Aug 18.
2
Comparative analysis between interstitial brachytherapy and stereotactic body irradiation for local ablation in liver malignancies.肝恶性肿瘤局部消融的组织间近距离放疗与立体定向体部放疗的对比分析
Brachytherapy. 2019 Nov-Dec;18(6):823-828. doi: 10.1016/j.brachy.2019.08.003. Epub 2019 Sep 12.
3
Brachytherapy: A critical component of primary radiation therapy for cervical cancer: From the Society of Gynecologic Oncology (SGO) and the American Brachytherapy Society (ABS).
近距离放射治疗：宫颈癌放射治疗的重要组成部分：来自妇科肿瘤学会（SGO）和美国近距离放射治疗学会（ABS）。
Gynecol Oncol. 2019 Mar;152(3):540-547. doi: 10.1016/j.ygyno.2018.10.016. Epub 2019 Jan 18.
4
Dosimetric comparison of vaginal vault brachytherapy vs applicator-guided stereotactic body radiotherapy with volumetric modulated arc therapy and helical tomotherapy for endometrium cancer patients.子宫内膜癌患者阴道穹窿近距离放疗与施源器引导立体定向体部放疗联合容积调强弧形放疗和螺旋断层放疗的剂量学比较
Med Dosim. 2019;44(4):332-338. doi: 10.1016/j.meddos.2018.11.005. Epub 2018 Dec 11.
5
Iridium-Knife: Another knife in radiation oncology.铱刀：放射肿瘤学中的又一利器。
Brachytherapy. 2017 Jul-Aug;16(4):884-892. doi: 10.1016/j.brachy.2017.03.005. Epub 2017 Apr 6.
6
The impact of hypoxia and its modification of the outcome of radiotherapy.缺氧的影响及其对放射治疗结果的改变。
J Radiat Res. 2016 Aug;57 Suppl 1(Suppl 1):i90-i98. doi: 10.1093/jrr/rrw007. Epub 2016 Mar 16.
7
Dosimetric comparison of brachyablation and stereotactic ablative body radiotherapy in the treatment of liver metastasis.近距离消融与立体定向消融体部放射治疗在肝转移瘤治疗中的剂量学比较
Brachytherapy. 2015 Jul-Aug;14(4):537-42. doi: 10.1016/j.brachy.2015.04.002. Epub 2015 May 2.
8
Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions.消融性肿瘤放疗可改变肿瘤免疫细胞微环境以诱导持久的完全缓解。
Clin Cancer Res. 2015 Aug 15;21(16):3727-39. doi: 10.1158/1078-0432.CCR-14-2824. Epub 2015 Apr 13.
9
National Cancer Data Base analysis of radiation therapy consolidation modality for cervical cancer: the impact of new technological advancements.国家癌症数据库分析宫颈癌放疗巩固方式：新技术进步的影响。
Int J Radiat Oncol Biol Phys. 2014 Dec 1;90(5):1083-90. doi: 10.1016/j.ijrobp.2014.07.017. Epub 2014 Sep 9.
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Dosimetry analyses comparing high-dose-rate brachytherapy, administered as monotherapy for localized prostate cancer, with stereotactic body radiation therapy simulated using CyberKnife.剂量学分析比较了高剂量率近距离放射治疗（作为局限性前列腺癌的单一疗法）与使用射波刀模拟的立体定向体部放射治疗。
J Radiat Res. 2014 Nov;55(6):1114-21. doi: 10.1093/jrr/rru048. Epub 2014 Jun 23.