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[胃黏膜与抗炎药。纤维内镜比较研究]

[Gastric mucosa and anti-inflammatory agents. A comparative study by fibroscopy].

作者信息

Rampon S, Bussière J L, Lopitaux R, Sauvezie B, Fermaud H, Rivoal A, Bergeron A

出版信息

Rev Rhum Mal Osteoartic. 1978 Mar;45(3):153-60.

PMID:306658
Abstract

A comparison was made between the gastroduodenal lesions observed by fibroscopy in a group of 47 patients treated with anti-inflammatory drugs for rheumatic conditions and a group of 50 controls. All patients had clinical symptoms of the stomach or duodenum. A statistical study show that the two groups were similar as regards age, sex and clinical signs. Besides ulcers the gastroduodenal lesions were acute and/or chronic. Among acute gastritis forms distinction is made between superficial, muco-erosive and haemorrhagic gastritis. The study showed the very high frequency of lesions of acute gastritis in rheumatic patients, especially of the antral and muco-erosive types, whereas the incidence of gastroduodenal ulcers was no higher than in the controles. An important finding is that acute gastritis is not favoured by pre-existing chronic gastritis.

摘要

对一组47例接受抗炎药物治疗风湿性疾病的患者和一组50例对照者进行了纤维胃镜检查观察到的胃十二指肠病变的比较。所有患者均有胃或十二指肠的临床症状。一项统计研究表明,两组在年龄、性别和临床体征方面相似。除溃疡外,胃十二指肠病变为急性和/或慢性。在急性胃炎类型中,区分了浅表性、黏液糜烂性和出血性胃炎。研究表明,风湿性患者急性胃炎病变的发生率非常高,尤其是胃窦部和黏液糜烂性类型,而胃十二指肠溃疡的发生率并不高于对照组。一个重要的发现是,既往存在的慢性胃炎并不会增加急性胃炎的发病风险。

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