Spencer E S, Fjeldborg O, Mordhorst C H
Medical Department C and Surgical Department T, Arhus Kommunehospital, Denmark.
Dan Med Bull. 1988 Oct;35(5):499-500.
Active infection with one of the herpes viruses, Cytomegalovirus, clearly worsens renal allograft survival. In the present study serologic evidence of infection with another herpes virus, Herpes simplex, was compared with graft survival in 89 cadaveric renal graft recipients transplanted during a two-year period at the Aarhus Center. With respect to Herpes simplex complement-fixing serum antibody status post-transplant, three groups could be identified: 1) No change in antibody titer (25 patients); 2) Significant (4-fold) or more antibody rises (41 patients); 3) No demonstrable antibody (23 patients). Actuarial graft survival was not significantly different in the three groups and thus Herpes simplex infection, in contrast to Cytomegalovirus, does not appear to influence the outcome of renal allograft transplantation.
感染疱疹病毒之一的巨细胞病毒，显然会使肾移植的存活率恶化。在本研究中，对另一种疱疹病毒单纯疱疹病毒感染的血清学证据与在奥胡斯中心两年期间接受移植的89例尸体肾移植受者的移植存活率进行了比较。根据移植后单纯疱疹病毒补体结合血清抗体状态，可分为三组：1）抗体滴度无变化（25例患者）；2）抗体显著（4倍）或更高升高（41例患者）；3）无可检测抗体（23例患者）。三组的移植存活率无显著差异，因此与巨细胞病毒不同，单纯疱疹病毒感染似乎不会影响肾移植的结果。
