Cha Jeeyeon, Khurram Muhammad, Gellert Lan, Epstein Paul, Baregamian Naira, Hendrickson Chase
Department of Medicine, Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, TN, USA.
Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
J Clin Transl Endocrinol Case Rep. 2018 Dec;10:1-3. doi: 10.1016/j.jecr.2018.07.003. Epub 2018 Aug 2.
Pheochromocytomas have been shown to impair glucose tolerance and, rarely, to precipitate overt diabetes mellitus. We report here a case of a large pheochromocytoma in a woman with a recent diagnosis of diabetes mellitus that proved difficult to control despite high-dose insulin therapy who had complete resolution of her hyperglycemia following adrenalectomy. Her dramatic presentation demonstrates the need to consider this etiology in patients with new-onset insulin resistance and hypertension.
嗜铬细胞瘤已被证明会损害糖耐量,且很少会引发显性糖尿病。我们在此报告一例患有大嗜铬细胞瘤的女性病例,该女性近期被诊断为糖尿病,尽管接受了高剂量胰岛素治疗,但其血糖仍难以控制,而肾上腺切除术后她的高血糖症状完全缓解。她的显著表现表明,对于新发胰岛素抵抗和高血压患者,有必要考虑这种病因。