人类口腔菌群中的腐蚀艾肯菌

Eikenella corrodens in human mouth flora.

作者信息

Rayan G M, Putnam J L, Cahill S L, Flournoy D J

机构信息

Orthopaedic Surgery Department, University of Oklahoma Health Sciences Center, Oklahoma City.

出版信息

J Hand Surg Am. 1988 Nov;13(6):953-6. doi: 10.1016/0363-5023(88)90279-1.

DOI:10.1016/0363-5023(88)90279-1

PMID:3066818

Abstract

The incidence of Eikenella corrodens in the human mouth was studied in 229 individuals. Six (2.6%) had positive cultures. The incidence of positive cultures for the saliva group was 0.6% and for the tooth-scraping group it was 8.2%. When 11 isolates were tested against 33 antimicrobials by disc-agar diffusion, 82% were susceptible to penicillin, cephalothin, and cefoperazone. Susceptibility to the remaining second- and third-generation cephalosporins studied was 100%. We suggest that the use of a second- or third-generation cephalosporin only is appropriate empiric therapy for human bite injuries.

摘要

在229名个体中研究了啮蚀艾肯菌在人口腔中的发生率。6人（2.6%）培养结果呈阳性。唾液组培养阳性率为0.6%，刮牙组为8.2%。当通过纸片琼脂扩散法对11株分离菌进行33种抗菌药物测试时，82%对青霉素、头孢噻吩和头孢哌酮敏感。对其余研究的第二代和第三代头孢菌素的敏感性为100%。我们建议，对于人类咬伤，仅使用第二代或第三代头孢菌素是合适的经验性治疗方法。