Foshan Institute of Fetal Medicine, Southern Medical University Affiliated Maternal and Child Health Hospital of Foshan, Foshan, Guangdong, China.
Department of Epidemiology, School of Basic Medicine, Jinan University, Guangzhou, Guangdong, China.
Am J Hypertens. 2019 Apr 22;32(5):492-502. doi: 10.1093/ajh/hpz003.
Hypertension is a growing problem worldwide and can often result in a variety of negative health outcomes. The aim of this study was to assess the effects of age at diagnosis, calendar period, and birth cohort on the change in the prevalence rate of hypertension in Guangzhou from 2004 to 2013.
We used data from the Guangzhou Community Health Survey, a population-based study designed by the National Health and Family Planning Commission of the PRC every 5 years. A total of 27,299, 23,467, and 18,362 participants aged 15-79 years completed the survey in 2004, 2009, and 2013, respectively.
Age effects increased slowly before the age of 42 years but increased rapidly after the age of 42 years, peaking at 79 years. Cohort effects grew slowly before the end of the 1960s but grew quickly after the end of the 1960s. The risk of suffering from hypertension among people born in 1962, 1972, 1982, and 1992 was 1.39, 2.68, 5.55, and 11.53 times, respectively, than that of people born in 1952. The period effects increased 25% from 2004 to 2009 and later declined 27% from 2009 to 2013 in the entire population. There was no gender difference in age effects and period effects, but strong cohort effects on hypertension were observed among males compared with females.
For Chinese individuals, the later one is born, the higher the risk is of suffering from hypertension. Strong cohort effects for hypertension were observed among males compared with females, indicating that males are more easily affected by hypertension based on the change in birth cohort.
高血压是全球范围内日益严重的问题,通常会导致多种负面健康后果。本研究旨在评估诊断时的年龄、时间区间和出生队列对 2004 年至 2013 年广州高血压患病率变化的影响。
我们使用了中国国家卫生和计划生育委员会每 5 年进行一次的全国性社区卫生调查(Guangzhou Community Health Survey)的数据。共有 27299、23467 和 18362 名 15-79 岁的参与者分别于 2004 年、2009 年和 2013 年完成了调查。
年龄效应在 42 岁之前缓慢增加,但在 42 岁之后迅速增加,在 79 岁时达到峰值。队列效应在 20 世纪 60 年代末之前缓慢增长,但在 20 世纪 60 年代末之后迅速增长。出生于 1962 年、1972 年、1982 年和 1992 年的人群患高血压的风险分别是出生于 1952 年人群的 1.39、2.68、5.55 和 11.53 倍。2004 年至 2009 年期间,整个人群的时期效应增加了 25%,2009 年至 2013 年期间又下降了 27%。年龄效应和时期效应在性别间没有差异,但男性中高血压的队列效应明显强于女性。
对于中国个体而言,出生越晚,患高血压的风险越高。与女性相比,男性中高血压的队列效应更强,这表明基于出生队列的变化,男性更容易受到高血压的影响。