[代谢综合征伴突发性感音神经性听力损失的临床特征及预后分析]

[Clinical characteristics and prognostic analysis of sudden sensorineural hearing loss with metabolic syndrome].

作者信息

Shi D Z, Zou S C, Ai W B

机构信息

Department of Otolaryngology Head and Neck Surgery, the Second Affiliated Hospital of University of South China, Hengyang, 421001, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jan;33(1):63-66. doi: 10.13201/j.issn.1001-1781.2019.01.013.

DOI:10.13201/j.issn.1001-1781.2019.01.013

Abstract

To analyze the clinical characteristics and prognosis of sudden sensorineural hearing loss (SSNHL) with metabolic syndrome (MetS).Records of 212 patients with SSNHL treated in our department were retrospectively reviewed, including gender, age,course of the disease, concomitant time of tinnitus and vertigo, concomitant rate of hypertension and diabetes mellitus, BMI, systolic pressure, diastolic pressure, HDL-C, TG, fasting plasma glucose level, severity of hearing loss and audiograms. All patients were divided into two groups, the MetS group and the Non-MetS group, and the clinical characteristics and prognosis between two groups were compared.In the MetS group, the BMI, systolic pressure, TG, fasting plasma glucose level were higher than that in the Non-MetS group, while the HDL-C level was lower than that in Non-MetS group (<0.01), and the rates of profound hearing loss, flat audiogram and total deafness audiogram were higher than that in the Non-MetS group (<0.05). In the MetS group, the overall recovery rate, complete recovery rate and marked recovery rate were 57.8%,6.0% and 14.5%, respectively, which was lower than that in the Non-MetS group (79.8%,19.4% and 27.9%, <0.05 ).SSNHL patients with MetS suffered a severer hearing loss, the most audiograms were flat and total deafness, and the prognosis of SSNHL patients with MetS was poorer.

摘要

分析伴代谢综合征（MetS）的突发性感音神经性听力损失（SSNHL）的临床特征及预后。回顾性分析我科收治的212例SSNHL患者的病历资料，内容包括性别、年龄、病程、耳鸣及眩晕伴随时间、高血压及糖尿病伴随率、BMI、收缩压、舒张压、高密度脂蛋白胆固醇（HDL-C）、甘油三酯（TG）、空腹血糖水平、听力损失严重程度及听力图。将所有患者分为两组，即MetS组和非MetS组，比较两组的临床特征及预后。MetS组的BMI、收缩压、TG、空腹血糖水平高于非MetS组，而HDL-C水平低于非MetS组（<0.01），重度听力损失、听力图平坦及全聋听力图的发生率高于非MetS组（<0.05）。MetS组的总体恢复率、完全恢复率及显著恢复率分别为57.8%、6.0%和14.5%，低于非MetS组（79.8%、19.4%和27.9%，<0.05）。伴MetS的SSNHL患者听力损失更严重，多数听力图为平坦型及全聋型，且伴MetS的SSNHL患者预后较差。