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一项关于芳香疗法治疗术后恶心和呕吐的随机安慰剂对照研究。

A randomized placebo-controlled study of aromatherapy for the treatment of postoperative nausea and vomiting.

机构信息

Department of Anesthesiology and Reanimation, School of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey.

Department of Anesthesiology and Reanimation, School of Medicine, Tokat Gaziosmanpasa University, Tokat, Turkey.

出版信息

Complement Ther Med. 2019 Feb;42:417-421. doi: 10.1016/j.ctim.2018.12.019. Epub 2018 Dec 28.

Abstract

OBJECTIVE

The purpose of this study was to compare the aromatherapy treatment effects on PONV patients using ginger, lavender and rose oils and a placebo.

DESIGN

A randomized 4-armed placebo controlled study.

SETTING

Gaziosmanpasa University, School of Medicine, Health Research and Application Center.

INTERVENTION

The total of 184 patients were randomized into 4 groups: Aromatherapy with lavender essential oil (Lavender group), with rose essential oil (Rose group), with ginger essential oil (Ginger group) or with pure water (Placebo group).

MAIN OUTCOME MEASURES

Postoperative nausea (0-3 Likert type; 0=no nausea, 1=some, 2=a lot, 3=severe) and vomiting scores (0-3 Likert type; 0=no vomiting, 1 = 1 time, 2 = 2 or 3 time, 3 = 4 times and up) and antiemetic medication requirement.

RESULTS

The nausea scores at 15 min were statistically significantly different between the groups (p = 0.00). The postoperative nausea scores improved in 20 (43.5%) subjects in the placebo group, 38 (82.6%) subjects in the lavender group, 22 (47.8%) subjects in the rose group and 30 (65.2%) subjects in the ginger group (p = 0.00). There were statistically significant differences between the groups with regard to the vomiting and antiemetic drug requirements (p = 0.00).

CONCLUSION

The aromatherapy can be used as an alternative or complementary method for managing PONV. Specifically, the ginger and lavender essential oils were superior to the rose oil and pure water for the aromatherapy treatments. However, further studies with larger sample sizes are necessary to confirm these results.

摘要

目的

本研究旨在比较生姜、薰衣草和玫瑰精油与安慰剂对 PONV 患者的治疗效果。

设计

一项随机 4 臂安慰剂对照研究。

地点

加济安泰普大学医学院健康研究与应用中心。

干预

共有 184 名患者随机分为 4 组:薰衣草精油芳香疗法(薰衣草组)、玫瑰精油芳香疗法(玫瑰组)、生姜精油芳香疗法(生姜组)或纯水(安慰剂组)。

主要观察指标

术后恶心(0-3 级 Likert 量表;0=无恶心,1=有些,2=很多,3=严重)和呕吐评分(0-3 级 Likert 量表;0=无呕吐,1=1 次,2=2 或 3 次,3=4 次及以上)和止吐药需求。

结果

15 分钟时,各组间恶心评分存在统计学差异(p=0.00)。安慰剂组 20 例(43.5%)、薰衣草组 38 例(82.6%)、玫瑰组 22 例(47.8%)和生姜组 30 例(65.2%)患者术后恶心评分改善。在呕吐和止吐药需求方面,各组间存在统计学差异(p=0.00)。

结论

芳香疗法可作为防治 PONV 的一种替代或补充方法。具体而言,生姜和薰衣草精油在芳香疗法治疗中优于玫瑰油和纯水,但需要更大样本量的进一步研究来证实这些结果。

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