Department of Medicine, Surgery and Health Sciences, University of Trieste, Via dell'Istria 65/1, 34137, Trieste, Italy.
Department of Pediatrics, Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, Italy.
Eur J Pediatr. 2019 Apr;178(4):587-591. doi: 10.1007/s00431-019-03320-z. Epub 2019 Jan 22.
Procedural sedation and analgesia with ketamine are part of daily practice for children undergoing painful procedures in the paediatric emergency department (ED) of North America. A massive number of studies demonstrate ketamine's safety and efficacy in the hands of trained ED paediatricians, with few severe adverse events (SAEs) recorded. Since there are no data on ketamine's usage in Italian paediatric EDs, we created a survey to examine procedural sedation with ketamine in the EDs of the Italian PIPER (Pain in Paediatric Emergency Room) group, which includes 36 paediatric EDs providing 1.4 million paediatric visits each year. Results were reviewed using frequencies to describe responses. Thirty-two out of 36 centres replied to the questionnaire. In 6 (19%) out of 32 centres, ketamine is not used at all in the paediatric ED. In 6 centres (23%) of 26 which use ketamine, this drug is autonomously administered by the emergency paediatrician, whereas in 20 (77%) of them it is exclusively managed by the anaesthesiologist on call.Conclusion: ketamine is autonomously administered only by a small percentage of Italian emergency paediatricians. There is an increasing need for implementation of procedural sedation training and use of ketamine in the everyday practice outside the operating room in paediatric EDs. What is Known: • Ketamine is safely and efficaciously administered for children's procedural sedation and analgesia by trained emergency paediatricians in the everyday practice outside the operating room in North America. • In the Italian setting, there are no data at all concerning ketamine's usage by the emergency paediatricians for procedural sedation and pain control. What is New: • In this study emerged that ketamine is poorly administered by Italian emergency paediatricians for procedural sedation and analgesia outside the operating room. • A great deal of educational effort should be made to widen ketamine based procedural sedation availability in Italian emergency departments by spreading specific training tracks and guidelines.
在北美的儿科急诊部门(ED),对接受痛苦程序的儿童进行氯胺酮程序性镇静和镇痛是日常实践的一部分。大量研究表明,在经过培训的 ED 儿科医生手中,氯胺酮具有安全性和有效性,记录到的严重不良事件(SAE)很少。由于意大利儿科 ED 没有关于氯胺酮使用的数据,我们创建了一项调查,以检查意大利 PIPER(儿科急诊室疼痛)小组的 ED 中使用氯胺酮进行的程序镇静,该小组包括 36 个提供每年 140 万儿科就诊的儿科 ED。使用频率来描述反应来审查结果。36 个中心中有 32 个回复了问卷。在 32 个中心中的 6 个(19%)中,儿科 ED 根本不使用氯胺酮。在 26 个使用氯胺酮的中心中的 6 个(23%)中,这种药物由急诊儿科医生自主管理,而在其中 20 个(77%)中,它完全由值班麻醉师管理。结论:只有一小部分意大利急诊儿科医生自主使用氯胺酮。在儿科 ED 手术室之外的日常实践中,越来越需要实施程序性镇静培训和使用氯胺酮。已知:• 在北美的日常实践中,经过培训的急诊儿科医生安全有效地为儿童进行程序性镇静和镇痛,使用氯胺酮。• 在意大利,关于急诊儿科医生使用氯胺酮进行程序性镇静和疼痛控制,没有任何数据。新内容:• 在这项研究中,意大利急诊儿科医生在手术室外为儿童进行程序性镇静和镇痛时,氯胺酮的使用情况较差。• 应该做出大量的教育努力,通过传播特定的培训课程和指南,扩大意大利急诊部门基于氯胺酮的程序性镇静的可用性。