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自血穴位注射疗法治疗痤疮的疗效与安全性:系统评价

[Efficacy and safety of autohemotherapy at acupoint for acne: systematic review].

作者信息

Li Caicai, Wang Shaojun

机构信息

Dermatology Department of Acupuncture-Moxibustion Hospital, China Academy of Chinese Medical Sciences, Beijing 100700, China.

出版信息

Zhongguo Zhen Jiu. 2018 Oct 12;38(10):1135-9. doi: 10.13703/j.0255-2930.2018.10.029.

Abstract

OBJECTIVE

To evaluate the efficacy and safety of autohemotherapy at acupoint for acne.

METHODS

Randomized controlled trials (RCTs) regarding autohemotherapy at acupoint for acne were searched in CNKI, WanFang, VIP database and PubMed. According to the inclusion and exclusion criteria, two investigators performed the literature screening, data extraction and basis evaluation, independently. Meta analysis was performed by using Review Manager 5.3 software.

RESULTS

Eight RCTs were included, involving 573 patients. The combined effect of effective rate was 1.21 (95% : 1.12, 1.30); the combined effect of skin lesions improvement was -1.00 (95%: -2.14, -0.14, =1.73, =0.08); the combined effect of recurrence rate was 0.44 (95%: 0.09, 2.15, =1.01, =0.31).

CONCLUSION

The autohemotherapy at acupoint has better efficacy and skin lesions improvement for acne than control treatment, and autohemotherapy is safer.

摘要

目的

评估穴位自血疗法治疗痤疮的疗效和安全性。

方法

在知网、万方、维普数据库及PubMed中检索关于穴位自血疗法治疗痤疮的随机对照试验(RCT)。根据纳入和排除标准,由两名研究者独立进行文献筛选、数据提取及基线评估。采用RevMan 5.3软件进行Meta分析。

结果

纳入8项RCT,共573例患者。有效率合并效应值为1.21(95%CI:1.12,1.30);皮损改善合并效应值为-1.00(95%CI:-2.14,-0.14,I²=1.73,P=0.08);复发率合并效应值为0.44(95%CI:0.09,2.15,I²=1.01,P=0.31)。

结论

穴位自血疗法治疗痤疮的疗效及皮损改善情况优于对照治疗,且穴位自血疗法更安全。

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