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预测医学时代的植入前基因诊断(PGD)

[Preimplantation genetic diagnosis (PGD) in the era of predictive medicine].

作者信息

Baertschi Bernard

机构信息

Institut Éthique, Histoire, Humanités (iEH2), université de Genève, CMU, 1 rue Michel-Servet, CP 1211 Genève 4, Suisse.

出版信息

Med Sci (Paris). 2019 Jan;35(1):72-77. doi: 10.1051/medsci/2018292. Epub 2019 Jan 23.

Abstract

High speed sequencing is revolutionizing the various genetic tests and in particular preimplantation genetic diagnosis (PGD), opening the doors to an increasingly efficient predictive medicine. PGD itself is not new, and the various legistations have been dealing with it for some twenty years. National ethics committees, for their part, have widely debated antenatal tests in the context of medically assisted procreation. This paper examines the work of these Committees on PGD in three States, France, Belgium and Switzerland, in order to highlight their similarities and differences. The subject has also been raised and discussed in the context of the États généraux de la bioéthique which took place this year in France and, given the progresses made recently, they have echoed certain demands of civil society. However, in France, caution continues to dominate.

摘要

高速测序正在彻底改变各种基因检测,尤其是植入前基因诊断(PGD),为日益高效的预测医学打开了大门。PGD本身并不新鲜,各种立法机构已经处理这个问题约二十年了。国家伦理委员会则在医学辅助生殖的背景下广泛讨论了产前检测。本文研究了法国、比利时和瑞士这三个国家的委员会在PGD方面的工作,以突出它们的异同。今年在法国举行的生物伦理大会也提出并讨论了这个问题,鉴于最近取得的进展,这些讨论回应了民间社会的某些要求。然而,在法国,谨慎态度仍然占据主导。

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