SUNY Downstate Medical Center, Brooklyn, NY, United States.
SUNY Downstate Medical Center, Brooklyn, NY, United States.
Transplant Rev (Orlando). 2019 Jul;33(3):154-160. doi: 10.1016/j.trre.2019.01.001. Epub 2019 Jan 14.
Dual kidney transplantation (DKT) is a viable option to increase the donor pool and improve access equity to kidney transplantation. Dual kidneys are procured from carefully selected marginal donors that are not generally acceptable to most transplant centers. This is a narrative review of literature focusing on donor kidney allocation systems and selection of the ideal recipient for DKT. We also discussed surgical approaches for DKTs as well as patient and allograft outcomes. We found that most studies to date showed that DKTs has similar graft survival and delayed graft function rates when compared to single kidney transplants (SKTs). DKT is technically feasible with outcomes that are comparable to expanded criteria donor kidneys (ECD); and has substantial potential in expanding the donor pool. For allograft survival, most studies with strict allocation criteria showed that graft survival was similar in DKT as compared to SKT - ECD transplants.. Our review may encourage transplant centers to review their policies for donor and recipient selection leading to increase in DKT.
双肾移植（DKT）是增加供体库并改善肾移植公平准入的可行选择。双肾来自经过精心挑选的边缘供体，这些供体通常不被大多数移植中心接受。本文是对文献的叙述性综述，重点介绍了供体肾脏分配系统和 DKT 理想受者的选择。我们还讨论了 DKT 的手术方法以及患者和移植物的结果。我们发现，迄今为止的大多数研究表明，与单肾移植（SKT）相比，DKT 的移植物存活率和延迟移植物功能率相似。DKT 在技术上是可行的，其结果与扩展标准供体肾脏（ECD）相当，并且在扩大供体库方面具有很大的潜力。对于移植物存活率，大多数采用严格分配标准的研究表明，与 SKT-ECD 移植相比，DKT 的移植物存活率相似。我们的综述可能会鼓励移植中心审查其供体和受者选择政策，从而增加 DKT 的数量。
