Shah Sonal S, Moustafa Tamer Zayed
New York University College of Dentistry, 345 E 24th St, Room 837, NY, New York 10010, USA.
Case Rep Dent. 2018 Dec 25;2018:2052347. doi: 10.1155/2018/2052347. eCollection 2018.
Salivary gland tumors are relatively common in the junction of the hard and soft palate area of the oral cavity. Pleomorphic adenoma is considered the most common benign salivary gland tumor in this location. Some of the rarer subtypes of this tumor may have a misleading clinical presentation. Recognition of these variants is important since long-standing pleomorphic adenomas have the potential to become malignant.
A healthy 24-year-old male was referred for a painless, large, slowly growing, exophytic swelling of the right hard and soft palate. Interestingly, the lesion was yellowish in color and soft to palpation, suggestive of an innocuous lipoma or cystic lesion. An incisional biopsy was performed and the diagnosis was consistent with pleomorphic adenoma with a significant adipose tissue component. The patient was referred to an oral surgeon and underwent a complete surgical excision. Upon two-year follow-up, the patient is doing well with no recurrences.
This case highlights a rare microscopic variant of pleomorphic adenoma with altered clinical presentation that led to an erroneous clinical diagnosis. The importance of taking a biopsy for definitive diagnosis and appropriate management is reinforced.
涎腺肿瘤在口腔硬腭和软腭交界处相对常见。多形性腺瘤被认为是该部位最常见的涎腺良性肿瘤。该肿瘤的一些较罕见亚型可能具有误导性的临床表现。认识这些变异型很重要，因为长期存在的多形性腺瘤有可能恶变。
一名24岁健康男性因右硬腭和软腭出现无痛性、巨大、生长缓慢的外生性肿物而前来就诊。有趣的是，病变呈黄色，触诊柔软，提示为无害的脂肪瘤或囊性病变。进行了切开活检，诊断为多形性腺瘤伴大量脂肪组织成分。患者被转诊至口腔外科医生处，接受了完整的手术切除。经过两年随访，患者情况良好，无复发。
本病例突出了一种罕见的多形性腺瘤微观变异型，其临床表现改变导致了错误的临床诊断。强调了进行活检以明确诊断和进行适当治疗的重要性。
