J Assoc Nurses AIDS Care. 2019 May-Jun;30(3):292-300. doi: 10.1097/JNC.0000000000000052.
Viral suppression (VS) in patients newly diagnosed with HIV is critical to reducing morbidity, mortality, and new transmissions. Rapid initiation of antiretroviral therapy (ART) is a promising model to improve VS, but patients must be seen expeditiously by a prescribing provider. Our retrospective study compared patients achieving VS after introduction of medical visits on the same day as HIV diagnoses from 2014 to 2017. The time to VS was evaluated using survival analysis. Wilcoxon two-sample tests evaluated median times to VS (after diagnosis and ART receipt). When 2016-2017 was compared with 2014-2015, a higher proportion of patients achieved VS (96% and 90%, respectively; p = .0292); the median time to VS decreased to 88 from 101 days after diagnosis and to 44 from 70 days after receipt of ART. As clinicians consider rapid ART initiation, a medical visit on the same day as HIV diagnosis is an intermediate intervention that may improve VS.
新诊断出 HIV 的患者的病毒抑制(VS)对于降低发病率、死亡率和新的传播至关重要。快速启动抗逆转录病毒疗法(ART)是改善 VS 的一种很有前途的模式,但患者必须由处方提供者尽快就诊。我们的回顾性研究比较了 2014 年至 2017 年引入同日就诊模式后达到 VS 的患者。使用生存分析评估 VS 的时间。Wilcoxon 两样本检验评估了达到 VS 的中位时间(诊断和 ART 后)。与 2014-2015 年相比,2016-2017 年有更高比例的患者达到 VS(分别为 96%和 90%;p =.0292);诊断后达到 VS 的中位时间从 101 天降至 88 天,从接受 ART 后 70 天降至 44 天。随着临床医生考虑快速启动 ART,在 HIV 诊断同日就诊是一种中间干预措施,可能会提高 VS。