Department of Hand, Plastic and Reconstructive Surgery, BG Trauma Center Ludwigshafen, University of Heidelberg, Ludwig-Guttmann-Str. 13, Ludwigshafen, Germany.
Department of Medical Statistics, University Medicine Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1, Mannheim, Germany.
Microsurgery. 2020 Jan;40(1):12-18. doi: 10.1002/micr.30428. Epub 2019 Jan 24.
Limb salvage in patients with peripheral vascular disease (PVD) and soft tissue defects often requires both a restoration of blood flow to the lower extremity and soft tissue coverage. Outcomes of free tissue transfer may be affected by vein grafts, which can be used for the placement of an autologous venous bypass or an arteriovenous (AV) loop leading to different hemodynamic situations. The purpose of this study was to investigate whether free flap anastomosis to a bypass or an AV loop can be performed with comparable results.
We performed a matched-pair analysis of 22 patients with PVD undergoing free flap reconstructions of the lower extremity with end-to-side anastomosis to an autologous venous bypass (n = 11, 1 female and 10 male patients) or an AV loop (n = 11, 2 female and 9 male patients). Defects caused by trauma, infection, ulcer, or fasciotomy were reconstructed in each group with 5 muscle-based flaps, 3 parascapular flaps, 2 anterolateral thigh (ALT) flaps, and 1 conjoined latissimus dorsi and parascapular flap. Postoperative complications including thromboses, flap failures, wound complications, and hematomas were compared.
Postoperative complication rates including 1 venous pedicle thrombosis (9%vs. 0%, P = 1.0), minor (18% vs. 9%, P = 1.0) and major wound complications (45% vs. 27%, P = .69) as well as hematomas (27% vs. 36%, P = 1.0) did not show relevant differences between the groups. Flap failures were absent in both groups.
In patients with PVD, autologous venous bypass grafts may be used for end-to-side anastomoses of free flaps, with postoperative outcomes being comparable to AV loop reconstructions.
外周血管疾病(PVD)和软组织缺损患者的肢体保全通常需要恢复下肢的血流和软组织覆盖。游离组织转移的结果可能会受到静脉移植物的影响,这些移植物可用于放置自体静脉旁路或动静脉(AV)环,从而导致不同的血液动力学情况。本研究旨在探讨游离皮瓣吻合到旁路或 AV 环是否可以获得类似的结果。
我们对 22 例 PVD 患者进行了配对分析,这些患者行下肢游离皮瓣重建术,采用端侧吻合术将自体静脉旁路(n = 11,1 名女性和 10 名男性患者)或 AV 环(n = 11,2 名女性和 9 名男性患者)。每组均有 5 例肌肉皮瓣、3 例肩胛旁皮瓣、2 例股前外侧皮瓣和 1 例联合背阔肌和肩胛旁皮瓣,用于创伤、感染、溃疡或筋膜切开术后的缺损重建。比较术后并发症,包括血栓形成、皮瓣失败、伤口并发症和血肿。
术后并发症发生率包括 1 例静脉蒂血栓形成(9%对 0%,P = 1.0)、小并发症(18%对 9%,P = 1.0)和大伤口并发症(45%对 27%,P = 0.69)以及血肿(27%对 36%,P = 1.0),两组之间均无明显差异。两组均无皮瓣失败。
在 PVD 患者中,自体静脉旁路移植物可用于游离皮瓣的端侧吻合,术后结果与 AV 环重建相当。