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掌侧神经交叉移植术增强严重尺神经病变的感觉恢复。

Cross-Palm Nerve Grafts to Enhance Sensory Recovery in Severe Ulnar Neuropathy.

机构信息

Washington University School of Medicine in St. Louis, MO, USA.

出版信息

Hand (N Y). 2020 Jul;15(4):526-533. doi: 10.1177/1558944718822851. Epub 2019 Jan 24.

Abstract

Intrinsic atrophy and debilitating sensory loss are prominent features of severe ulnar neuropathy with limited surgical options to reliably improve recovery. Restoration of sensation is important to provide protection for the vulnerable ulnar border of the hand. Here, we report our experience with side-to-side sensory nerve grafting from the median to ulnar nerve in the palm to enhance ulnar sensory recovery. A retrospective chart review identified patients with severe ulnar neuropathy who underwent cross-palm nerve grafting. Included patients had objective loss of protective sensation in the ulnar distribution with 2-point discrimination >8 mm, Semmes-Weinstein monofilament testing (SWMT) >4.56, or no sensory response on nerve conduction testing. Cross-palm side-to-side tension-free grafting from median to ulnar sensory components was performed using short-segment allograft or autografts. Analysis included patient etiology, procedures, nerve conduction studies, objective sensory testing, and Disabilities of the Arm, Shoulder, and Hand Disability score. Forty-eight patients with severe ulnar neuropathy underwent cross-palm nerve grafting between 2014 and 2017. Twenty-four patients had adequate follow-up for inclusion. Of the 24 patients, 21 (87%) had return of protective sensation, 16 (66.7%) had return of diminished light touch sensation, and 6 (25%) had return to normal range sensation within 1 year as assessed by SWMT and/or 2-point discrimination. Patients treated with autograft demonstrated referred sensation to the median nerve distribution. Cross-palm nerve grafting may be a useful adjunct to enhance sensory recovery in severe ulnar neuropathy. Further study to quantify differences in sensory recovery between traditional operative techniques and cross-palm nerve grafting is required.

摘要

内在萎缩和使人衰弱的感觉丧失是严重尺神经病变的突出特征,手术选择有限,难以可靠地改善恢复。感觉的恢复对于保护手部脆弱的尺侧边缘很重要。在这里,我们报告了我们在手掌中从正中神经到尺神经进行侧侧感觉神经移植以增强尺神经感觉恢复的经验。

回顾性图表审查确定了接受过跨掌神经移植的严重尺神经病变患者。包括的患者在尺神经分布区有客观的保护感觉丧失,两点辨别> 8 毫米,Semmes-Weinstein 单丝测试(SWMT)> 4.56,或神经传导测试无感觉反应。使用短节段同种异体移植物或自体移植物进行从中正神经到尺神经感觉成分的跨掌侧侧无张力移植。分析包括患者病因、手术程序、神经传导研究、客观感觉测试和手臂、肩部和手残疾残疾评分。

2014 年至 2017 年间,48 例严重尺神经病变患者接受了跨掌神经移植。24 例患者有足够的随访纳入。在 24 例患者中,21 例(87%)有保护性感觉恢复,16 例(66.7%)有轻度触觉感觉恢复,6 例(25%)在 1 年内恢复正常范围感觉,通过 SWMT 和/或 2 点辨别评估。用自体移植物治疗的患者表现出正中神经分布的牵涉性感觉。

跨掌神经移植可能是增强严重尺神经病变感觉恢复的有用辅助手段。需要进一步研究以量化传统手术技术与跨掌神经移植之间感觉恢复的差异。

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