Reboli A C, Del Bene V E
Department of Medicine, Medical University of South Carolina, Charleston.
Dermatol Clin. 1988 Oct;6(4):497-520.
Oral antibiotics that may be useful in dermatology can be classified as beta-lactams (penicillins and cephalosporins), tetracyclines, macrolides, or quinolones; other options are clindamycin, trimethoprim-sulfamethoxazole, rifampin, and metronidazole. Proper understanding of the mechanisms of action and resistance, pharmacology, antimicrobial spectra, and adverse effects of these drugs will enable the clinician to obtain the best results.
在皮肤科可能有用的口服抗生素可分为β-内酰胺类(青霉素类和头孢菌素类)、四环素类、大环内酯类或喹诺酮类;其他选择包括克林霉素、甲氧苄啶-磺胺甲恶唑、利福平及甲硝唑。正确理解这些药物的作用机制、耐药性、药理学、抗菌谱及不良反应,将有助于临床医生取得最佳治疗效果。