Department of Healthcare, Guangdong Women and Children Hospital, No.521 Xingnan Road, Guangzhou, Guangdong, 511442, China.
Department of Physical Examination, Guangdong Women and Children Hospital, No.521 Xingnan Road, Guangzhou, Guangdong, 511442, China.
Sci Rep. 2019 Jan 24;9(1):757. doi: 10.1038/s41598-018-36758-6.
Mean birth weight of twins is known to be lower than that of singletons, however, southern China lacks a twin-specific birth weight reference. In this paper, we use data from the Birth Certificate System in southern China, collected between January 1 2014 and December 31 2017 and including 161,076 twins, to calculate sex- and gestational week-specific birth weight percentiles (the 3, 10, 25, 50, 75, 90, and 97). We applied generalized additive models for location, scale and shape (GAMLSS) when calculating the birth weight percentiles, and calculated percentiles for monochorionic and dichorionic twins separately. We next used data collected between Jan 1st 2018 and Apr 30th 2018, encompassing 12,371 live births, to calculate the SGA and LGA ratios using birth weight references in Australia, South Korea and China (based on birth defects surveillance system) and birth weight percentiles calculated in this study. Compared to dichorionic twins, monochorionic twins had lower birth weights at 25 to 42 weeks of gestation. The calculated SGA and LGA ratios were relatively stable compared to the other references.
双胞胎的平均出生体重低于单胎，但中国南方缺乏针对双胞胎的特定出生体重参考值。在本文中，我们使用了中国南方出生证系统的数据，该数据收集于 2014 年 1 月 1 日至 2017 年 12 月 31 日之间，包含 161076 对双胞胎，以计算性别和胎龄特异性出生体重百分位数（第 3、10、25、50、75、90 和 97 百分位）。我们在计算出生体重百分位数时应用了位置、尺度和形状的广义加性模型（GAMLSS），并分别为单绒毛膜和双绒毛膜双胞胎计算了百分位数。接下来，我们使用了 2018 年 1 月 1 日至 2018 年 4 月 30 日之间收集的数据，涵盖了 12371 例活产儿，使用澳大利亚、韩国和中国（基于出生缺陷监测系统）的出生体重参考值以及本研究中计算的出生体重百分位数，计算了 SGA 和 LGA 的比值。与双绒毛膜双胞胎相比，单绒毛膜双胞胎在 25 至 42 周的胎龄时出生体重较低。与其他参考值相比，计算出的 SGA 和 LGA 比值相对稳定。
