Shen Min-Hua, Huang Yuan-Liang, Li Zhen, Zhang Ying-di, He Yan-Ping, Wang Lei
Department Of Stomatology, Shanghai East Hospital Affiliated to Tongji University. Shanghai 200120, China. E-mail:
Shanghai Kou Qiang Yi Xue. 2018 Oct;27(5):508-512.
To evaluate the effect of platelet rich fibrin (PRF) combining with Bio-oss in treating Class II furcation involvement.
Thirty patients who had Class Ⅱ furcation involvement in the mandibular first molar were included. They were all free of systemic disease. After initial periodontal therapy, they were randomly divided into 2 groups. In the experimental group, PRF combining with Bio-oss were placed in the areas with furcation defect and covered with PRF. In the control group, only flap surgery was performed. All patients were followed up for 6 months after operation. The efficacy was evaluated with clinical parameters and cone-beam computed tomography (CBCT). The data were analyzed with SPSS 2.0 software package.
Periodontal indexes including probing depth (PD), clinical attachment loss (CAL), horizontal probing depth (HPD) significantly decreased in both groups after operation (P<0.05); alveolar bone significantly increased in the experimental group (P<0.05).
The clinical effect of PRF combined with Bio-oss on Class II furcation involvement are remarkable.
评估富血小板纤维蛋白（PRF）联合Bio-oss治疗Ⅱ度根分叉病变的效果。
纳入30例下颌第一磨牙Ⅱ度根分叉病变患者。他们均无全身疾病。在进行初始牙周治疗后，将他们随机分为2组。实验组在根分叉缺损区域放置PRF联合Bio-oss，并覆盖PRF。对照组仅进行翻瓣手术。所有患者术后随访6个月。采用临床参数和锥形束计算机断层扫描（CBCT）评估疗效。数据用SPSS 2.0软件包进行分析。
两组术后牙周指标包括探诊深度（PD）、临床附着丧失（CAL）、水平探诊深度（HPD）均显著降低（P<0.05）；实验组牙槽骨显著增加（P<0.05）。
PRF联合Bio-oss治疗Ⅱ度根分叉病变的临床效果显著。
