Department of Sense Organs, University Sapienza of Rome, Rome, Italy.
Cornea and Ocular Surface Unit, San Raffaele Hospital, Milan, Italy.
Pediatr Allergy Immunol. 2019 May;30(3):289-295. doi: 10.1111/pai.13024. Epub 2019 Feb 11.
Schoolchildren screening for allergic diseases may improve early identification and management of atopic children. The aim of this study was to perform a schoolchildren screening program for identification of children with allergic diseases.
All parents of children attending to 13 primary schools in the city of Rome were requested to fill in a demographic data form and the ChAt questionnaire. Allergological evaluation was performed in the children with suspect of allergy (ChAt score > 2). Ocular examination was performed to identify signs of allergic conjunctivitis. The presence of allergic symptoms was related to demographic and environmental variables.
A total of 2667 children (mean age: 7.1 ± 1 years) were included, and 2489 (93.3%) parents completed the ChAt questionnaire. Results of ChAt questionnaire showed a previous diagnosis of allergic disease in 637 (25.6%) children and the potential presence of an allergic disease (ChAt score > 2) in 35.1%. Multivariate analysis showed that older age, male gender, and having less than two siblings were associated with higher risk of allergic disease. Visual screening showed the presence of clinical signs of allergic conjunctivitis in 2% of children. Allergologic evaluation in 334 children confirmed the diagnosis of allergic disease in 324 (97%) cases. Among them, 97 (29.9%) did not refer to a previous formal diagnosis of allergic condition.
This study confirmed that schoolchildren screening using ChAt questionnaire could represent a useful tool for early identification of yet undiagnosed atopic children.
对过敏性疾病进行儿童筛查可能有助于早期识别和管理特应性儿童。本研究旨在开展儿童过敏筛查计划,以识别患有过敏性疾病的儿童。
要求罗马市 13 所小学的所有儿童家长填写人口统计学数据表格和 ChAt 问卷。对有过敏嫌疑的儿童(ChAt 评分>2)进行过敏评估。对有过敏症状的儿童进行眼部检查,以识别过敏性结膜炎的体征。将过敏症状的出现与人口统计学和环境变量相关联。
共纳入 2667 名儿童(平均年龄:7.1±1 岁),2489 名(93.3%)家长完成了 ChAt 问卷。ChAt 问卷结果显示,637 名(25.6%)儿童有既往过敏诊断,35.1%儿童有潜在过敏疾病(ChAt 评分>2)。多变量分析显示,年龄较大、男性和兄弟姐妹较少与过敏疾病风险增加相关。视觉筛查显示,2%的儿童有过敏性结膜炎的临床体征。对 334 名儿童进行过敏评估,在 324 名(97%)儿童中确认了过敏疾病的诊断。其中,97 名(29.9%)未提及以前曾被正式诊断为过敏。
本研究证实,使用 ChAt 问卷对儿童进行筛查可能是早期识别尚未确诊的特应性儿童的有用工具。