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游离双叶股前外侧皮瓣同期修复环状软骨及喉前皮肤受侵的局部复发性喉癌切除术后大的喉及喉前皮肤缺损:1例报告

Free bipaddled anterolateral thigh flap for simultaneous reconstruction of large larynx and prelaryngeal skin defects after resection of the local recurrent laryngeal cancer invading the cricoid cartilage and prelaryngeal skin: A case report.

作者信息

Liu Jun, Lv Dan, Deng Di, Wang Ji, Li Linke, Chen Fei

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Medicine (Baltimore). 2019 Jan;98(4):e14199. doi: 10.1097/MD.0000000000014199.

DOI:10.1097/MD.0000000000014199
PMID:30681591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6358393/
Abstract

RATIONALE

After total or near-total laryngectomy and resection of prelaryngeal skin, laryngeal defects and prelaryngeal skin defects often remain a great challenge for head and neck surgeons when considering simultaneous reconstruction of. In this case report, a free bipaddled anterolateral thigh (ALT) was used for such defects reconstruction.

PATIENT CONCERNS

For this 50-year-old male patient whose recurrent tumor invaded the cricoid cartilage and the prelaryngeal skin, supracricoid partial laryngectomy with a cricohyoidepiglottopexy would no longer be an option. However, the patient had a strong requirement of preserving lung-power speech, making total laryngectomy and chemoradiotherapy not acceptable.

DIAGNOSIS

Pathologic result demonstrated well-differentiated squamous cell carcinoma. A PET-CT of the whole body showed extralaryngeal extension of the tumor invading the cricoids cartilage and prelaryngeal ribbon muscles and skin. Meanwhile, the video-laryngoscpy showed smooth laryngeal mucosa.

INTERVENTIONS

A near-total laryngectomy and resection of prelaryngeal skin were performed. The resultant defects were reconstructed with a free bipaddled ALT flap.

OUTCOMES

The patient is 18 months postsurgery with no locoregion tumor recurrence, taking oral feeds, partial lung-power speech and not decannulated. Laryngostenosis was shown by the videolaryngoscopy, MRI and CT scan.

LESSONS

A free bipaddled ALT flap could be utilized for simultaneous reconstruction of large larynx and prelaryngeal skin defects, and allows partial laryngeal function preservation in selected local recurrent laryngeal cancer invading the cricoid cartilage and prelaryngeal skin.

摘要

原理

在全喉或近全喉切除及喉前皮肤切除术后,在考虑同时进行重建时,喉缺损和喉前皮肤缺损对头颈外科医生来说往往仍然是巨大的挑战。在本病例报告中,游离双叶股前外侧皮瓣(ALT)被用于此类缺损的重建。

患者情况

对于这位50岁的男性患者,其复发性肿瘤侵犯了环状软骨和喉前皮肤,环状软骨上部分喉切除术加环甲膜会厌固定术已不再是一种选择。然而,患者强烈要求保留肺动力性言语,这使得全喉切除术和放化疗无法接受。

诊断

病理结果显示为高分化鳞状细胞癌。全身PET-CT显示肿瘤超出喉外侵犯环状软骨、喉前带状肌和皮肤。同时,电子喉镜检查显示喉黏膜光滑。

干预措施

进行了近全喉切除及喉前皮肤切除。用游离双叶ALT皮瓣修复由此产生的缺损。

结果

患者术后18个月,局部无肿瘤复发,经口进食,有部分肺动力性言语,未拔管。电子喉镜检查、MRI和CT扫描显示有喉狭窄。

经验教训

游离双叶ALT皮瓣可用于同时修复大型喉和喉前皮肤缺损,并能在部分侵犯环状软骨和喉前皮肤的局部复发性喉癌患者中保留部分喉功能。

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本文引用的文献

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Salvage total laryngectomy after conservation laryngeal surgery for recurrent laryngeal squamous cell carcinoma.喉保留手术后复发性喉鳞状细胞癌的挽救性全喉切除术
Acta Otorhinolaryngol Ital. 2016 Oct;36(5):373-380. doi: 10.14639/0392-100X-749.
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Reconstruction of expanding tracheoesophageal fistulae in post-radiation therapy patients who undergo total laryngectomy with a bipaddled radial forearm free flap: Report of 8 cases.采用双叶桡侧前臂游离皮瓣对接受全喉切除术的放疗后患者扩张性气管食管瘘进行重建:8例报告
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