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剪接密码深似海。

The Splicing Code Goes Deep.

机构信息

Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA.

Department of Systems Biology, Department of Biochemistry and Molecular Biophysics, Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032, USA.

出版信息

Cell. 2019 Jan 24;176(3):414-416. doi: 10.1016/j.cell.2019.01.013.

Abstract

The importance of genomic sequence context in generating transcriptome diversity through RNA splicing is independently unmasked by two studies in this issue (Jaganathan et al., 2019; Baeza-Centurion et al., 2019).

摘要

这两期杂志中的两项研究(Jaganathan 等人,2019 年;Baeza-Centurion 等人,2019 年)独立揭示了基因组序列背景在通过 RNA 剪接产生转录组多样性方面的重要性。

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