Department of Otorhinolaryngology-Head and Neck Surgery, Chungbuk National University College of Medicine, Chungbuk National University Hospital, Cheongju, Republic of Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Dongguk University, Ilsan Hospital, Siksa-dong, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-773, Republic of Korea.
Eur Ann Otorhinolaryngol Head Neck Dis. 2019 Jun;136(3):199-201. doi: 10.1016/j.anorl.2018.03.009. Epub 2019 Jan 23.
Hypereosinophilic syndrome is a rare disease with hypereosinophilia resulting in end-organ dysfunction. Patients present with organ-associated symptoms, and the targets frequently affected are heart, lung, skin, or the nervous system, and the middle ear involvement is rare.
A 30-year-old female with left ear fullness and hearing loss, which persisted for 6months, was finally diagnosed with hypereosinophilic syndrome (HES). After high dose systemic steroids treatment, all symptoms improved.
Eosinophilic otitis media and HES involving the middle ear share many clinical manifestations. Prompt and accurate differential diagnosis is required for these diseases to ameliorate symptoms and promote recovery.
嗜酸性粒细胞增多综合征是一种罕见的疾病,其特征是嗜酸性粒细胞增多导致终末器官功能障碍。患者表现出与器官相关的症状,常受影响的靶器官为心脏、肺、皮肤或神经系统,中耳受累较为罕见。
一位 30 岁女性,左耳饱满伴听力下降,持续 6 个月,最终诊断为嗜酸性粒细胞增多综合征(HES)。经大剂量全身类固醇治疗后,所有症状均改善。
嗜酸性中耳炎和累及中耳的 HES 具有许多相似的临床表现。这些疾病需要及时准确地进行鉴别诊断,以改善症状并促进康复。