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支持性住房可促进有行为健康问题的长期无家可归的 HIV 阳性者实现艾滋病零死亡。

Supportive Housing Promotes AIDS-Free Survival for Chronically Homeless HIV Positive Persons with Behavioral Health Conditions.

机构信息

New York City Department of Health and Mental Hygiene, Office of School Health, 42-09 28th Street, CN-25, Queens, NY, 11101, USA.

New York City Department of Health and Mental Hygiene, Bureau of Epidemiology Services, 42-09 28th Street, Queens, NY, 11101, USA.

出版信息

AIDS Behav. 2019 Mar;23(3):776-783. doi: 10.1007/s10461-019-02398-8.

Abstract

We assessed the influence of supportive housing, incarceration, and health service use on markers of HIV infection for people living with HIV and serious mental illness or substance use disorder (SUD) participating in a New York City supportive housing program (NY III). Using matched administrative data from 2007 to 2014, we compared survivor time without AIDS, achievement of undetectable viral load, and maintenance of viral suppression between NY III tenants (n = 696), applicants placed in other supportive housing programs (n = 333), and applicants not placed in supportive housing (n = 268). Inverse probability of treatment weights were applied to Cox proportional hazards regression models to account for confounding of observed variables. Individuals not placed in supportive housing had a significantly greater risk of death or AIDS diagnosis than NY III tenants [adjusted hazard ratio = 1.84 (1.40, 2.44), p < 0.001]. Incarceration and outpatient SUD treatment were significantly associated with negative short-term outcomes (time to undetectable viral load) but positive long-term outcomes (time to death or AIDS diagnosis). Supportive housing, SUD treatment, and incarceration were associated with prolonged survival without AIDS among supportive housing applicants living with HIV.

摘要

我们评估了支持性住房、监禁和卫生服务利用对参与纽约市支持性住房项目(NY III)的艾滋病毒感染者和严重精神疾病或物质使用障碍(SUD)患者的艾滋病毒感染标志物的影响。利用 2007 年至 2014 年的匹配行政数据,我们比较了 NY III 租户(n=696)、被安置在其他支持性住房项目中的申请人(n=333)和未被安置在支持性住房中的申请人(n=268)之间无艾滋病的生存时间、实现不可检测的病毒载量和维持病毒抑制的情况。采用逆概率治疗权重对 Cox 比例风险回归模型进行分析,以解释观察变量的混杂。未被安置在支持性住房中的个体的死亡或艾滋病诊断风险明显高于 NY III 租户[校正风险比=1.84(1.40,2.44),p<0.001]。监禁和门诊 SUD 治疗与负面短期结果(病毒载量达到不可检测水平的时间)显著相关,但与正面长期结果(死亡或艾滋病诊断时间)显著相关。支持性住房、SUD 治疗和监禁与艾滋病毒感染者的支持性住房申请人无艾滋病生存时间延长有关。

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