Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Department of Medicine, Faculty of Medicine and Health Science, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.
J Pain Symptom Manage. 2019 Apr;57(4):802-808. doi: 10.1016/j.jpainsymman.2019.01.009. Epub 2019 Jan 24.
Dyspnea is a common and distressing symptom in respiratory diseases. Despite advances in the treatment of various lung diseases, the treatment modalities for dyspnea remain limited.
This study aims to examine the effect of 20-minute mindful breathing on the rapid reduction of dyspnea at rest in patients with lung cancer, chronic obstructive pulmonary disease, and asthma.
We conducted a parallel-group, nonblinded, randomized controlled trial of standard care plus 20-minute mindful breathing vs. standard care alone for patients with moderate to severe dyspnea due to lung disease, named previously, at the respiratory unit of University Malaya Medical Centre in Malaysia, from August 1, 2017, to March 31, 2018.
Sixty-three participants were randomly assigned to standard care plus a 20-minute mindful breathing session (n = 32) or standard care alone (n = 31), with no difference in their demographic and clinical characteristics. There was statistically significant reduction in dyspnea in the mindful breathing group compared with the control group at minute 5 (U = 233.5, n = 32, n = 31, mean rank = 23.28, mean rank = 37.72, z = -3.574, P < 0.001) and minute 20 (U = 232.0, n = 32, n = 31, mean rank = 23.00, mean rank = 36.77, z = -3.285, P = 0.001).
Our results provide evidence that a single session of 20-minute mindful breathing is effective in reducing dyspnea rapidly for patients with lung cancer, chronic obstructive pulmonary disease, and asthma.
呼吸困难是呼吸系统疾病中常见且令人痛苦的症状。尽管在治疗各种肺部疾病方面取得了进展，但呼吸困难的治疗方法仍然有限。
本研究旨在探讨 20 分钟正念呼吸对肺癌、慢性阻塞性肺疾病和哮喘患者静息时呼吸困难迅速缓解的影响。
我们在马来西亚大学医学中心的呼吸科进行了一项平行组、非盲、随机对照试验，纳入了因上述肺部疾病导致中重度呼吸困难的患者，在标准治疗的基础上，分别接受 20 分钟正念呼吸治疗（n=32）或单纯标准治疗（n=31）。
63 名参与者被随机分配到标准治疗加 20 分钟正念呼吸组（n=32）或单纯标准治疗组（n=31），两组的人口统计学和临床特征无差异。与对照组相比，正念呼吸组在第 5 分钟（U=233.5，n=32，n=31，平均秩=23.28，平均秩=37.72，z=-3.574，P<0.001）和第 20 分钟（U=232.0，n=32，n=31，平均秩=23.00，平均秩=36.77，z=-3.285，P=0.001）时呼吸困难显著降低。
我们的研究结果提供了证据，表明单次 20 分钟的正念呼吸可有效迅速减轻肺癌、慢性阻塞性肺疾病和哮喘患者的呼吸困难。
